Results 61 to 70 of about 18,104 (181)
Summary: Background: The full extent to which childhood pneumococcal conjugate vaccines (PCV) can indirectly reduce illness in unvaccinated populations is not known.
Tinevimbo Shiri, DrPhD +7 more
doaj +1 more source
ABSTRACT High‐energy open chest injuries with lung evisceration may be associated with concurrent injuries and serious potential sequelae including pneumocranium, brachial plexus injury, and venous thrombosis. Early resuscitation, adherence to ATLS principles, and coordinated multidisciplinary care are critical for survival and functional outcomes ...
Brian Kasagga +10 more
wiley +1 more source
Introduction: North American indigenous populations experience a high burden of invasive bacterial infections. Because Streptococcus pneumoniae and Haemophilus influenzae have multiple antigenic variants, the existing vaccines cannot prevent all cases ...
Vic Eton +5 more
doaj +1 more source
Invasive isolates of Streptococcus pneumoniae in Serbia: Antimicrobial susceptibility and serotypes [PDF]
Introduction. Streptococcus pneumoniae is one of the leading causes of bacterial meningitis and sepsis. Invasive pneumococcal disease is a significant medical problem worldwide, particularly in children, due to a huge increase of pneumococcal ...
Gajić Ina +5 more
doaj +1 more source
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom +4 more
wiley +1 more source
Preventing Invasive Pneumococcal Disease in Children [PDF]
Streptococcus pneumoniae is a major bacterial cause of sepsis, meningitis, and otitis media in infants and young children. In 1999, the Active Bacterial Core Surveillance Network reported a rate of invasive pneumococcal disease of 165.7 per 100,000 in children younger than 1 year old and a rate ...
openaire +2 more sources
ABSTRACT Background Non‐typeable Streptococcus pneumoniae (NT‐Sp) strains lack detectable capsules and are often missed by traditional serotyping. While associated primarily with asymptomatic carriage, NT‐Sp has emerged as a key player in antimicrobial resistance (AMR) gene dissemination and serotype replacement in the post‐vaccine era. This systematic
Robert K. Reeks +2 more
wiley +1 more source
Pneumococcal Polysaccharide Vaccination in Pediatric Inflammatory Bowel Disease
According to current recommendations, in addition to 13-valent pneumococcal conjugate vaccine (PCV13) series, all children with inflammatory bowel disease (IBD) aged ≥2 years, with planned or current immunosuppression, should receive pneumococcal ...
Tsega Temtem MD +2 more
doaj +1 more source
Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni +4 more
wiley +1 more source

