Results 51 to 60 of about 41,455 (247)

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]

, 2012
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu, A Kadioglu, A Nalbant, A Strasser, AD Badley, Andrea M. Mitchell, C Riccardi, CA Janeway Jr, CK Sung, D Zhou, David H. Dockrell, DH Dockrell, DH Dockrell, DH Dockrell, DR Cundell, EE McGrath, FK Swirski, Frank R. DeLeo, G Matute-Bello, Helen M. Marriott, HM Marriott, HM Marriott, I Nicoletti, J Warwick-Davies, JA Carrero, Julie A. Preston, K Beiter, K Kemp, K LeMessurier, KA Browne, KE Price, L Galluzzi, L Maggi, L Ziegler-Heitbrock, LA Kirkham, M Daigneault, M Lenardo, M Witzenrath, MA Barocchi, MA Bewley, Marc Daigneault, Martin A. Bewley, MJ Jedrzejas, Moira K. B. Whyte, N Olivares-Zavaleta, N Oyaizu, NV Serbina, PA Kiener, R Malley, RA Hirst, Robert C. Read, RS Hotchkiss, RS Hotchkiss, RS Hotchkiss, SE Weber, SJ Webster, SL Newman, T Mattern, T Takahashi, Thushan I. De Silva, Timothy J. Mitchell, WL Farrar, WP Hausdorff, YJ Lu, Z Zhang   +64 more
core   +4 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Predicting optimal impact interventions in the post‐HPV vaccination world

International Journal of Cancer, EarlyView.
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen, Marc Lipsitch, Ville N. Pimenoff, Karin Sundström, Johannes Berkhof, Iacopo Baussano, Simopekka Vänskä, Joakim Dillner   +7 more
wiley   +1 more source

Spontaneous pneumococcal peritonitis diagnosed by qPCR

IDCases, 2019
Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with
Daniel Jarovsky, Thais Grodzicki Ambrus, Mariana Galvão Gurgel, Marcelo Jenné Mimica, Mariana Volpe Arnoni, Flávia Jacqueline Almeida, Marco Aurélio Palazzi Sáfadi, Eitan Naaman Berezin   +7 more
doaj   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Changes in the incidence, viral coinfection pattern and outcomes of pneumococcal hospitalizations during and after the COVID-19 pandemic

Pneumonia
Background The incidence of pneumococcal pneumonia in the context of the Coronavirus Disease 2019 (COVID-19) pandemic, along with the real-world data on the ratio of non-invasive to invasive pneumococcal pneumonia, is an area that has not been thoroughly
King-Pui Florence Chan, Ting-Fung Ma, Hanshu Fang, Wai-Kai Tsui, James Chung-Man Ho, Mary Sau-Man Ip, Pak-Leung Ho   +6 more
doaj   +1 more source

Impact of Pneumococcal Conjugate Vaccines on Pneumonia Hospitalizations in High- and Low-Income Subpopulations in Brazil. [PDF]

, 2017
BackgroundPneumococcal conjugate vaccines (PCVs) are being used worldwide. A key question is whether the impact of PCVs on pneumonia is similar in low- and high-income populations.
Kürüm, Esra, Lustig, Roger, Schuck-Paim, Cynthia, Shioda, Kayoko, Simonsen, Lone, Taylor, Robert J, Warren, Joshua L, Weinberger, Daniel M   +7 more
core   +2 more sources

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Invasive pneumococcal disease surveillance in Canada, 2020

Canada Communicable Disease Report, 2022
Invasive pneumococcal disease (IPD), which is caused by Streptococcus pneumoniae, has been a nationally notifiable disease in Canada since 2000. The use of conjugate vaccines has markedly decreased the incidence of IPD in Canada; however, the distribution of serotypes has shifted in favour of non-vaccine types.
Alyssa, Golden, Averil, Griffith, Walter, Demczuk, Brigitte, Lefebvre, Allison, McGeer, Gregory, Tyrrell, George, Zhanel, Julianne, Kus, Linda, Hoang, Jessica, Minion, Paul, Van Caeseele, Hanan, Smadi, David, Haldane, George, Zahariadis, Kristen, Mead, Laura, Steven, Lori, Strudwick, Anita, Li, Michael, Mulvey, Irene, Martin   +19 more
openaire   +2 more sources