Results 51 to 60 of about 339,808 (204)

Epidemiological approaches to evaluate clinical unmasking of HPV‐associated cervical lesions in the HPV vaccination era

International Journal of Cancer, EarlyView.
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota, Jaimie Z. Shing, Jeffrey N. Roberts, Elizabeth M. Anderson, Alfred J. Saah, Ariana Harari, Eduardo L. Franco, Melvin Kohn, Susanne K. Kjær   +8 more
wiley   +1 more source

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

PROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland, Luke A. Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Emily J. Sunnucks, Sam T. Gould, Aleksandra M. Stanczak, Matthew B. O'Rourke, Matthew P. Padula   +9 more
wiley   +1 more source

Public health impact of pneumococcal conjugate vaccine infant immunization programs: assessment of invasive pneumococcal disease burden and serotype distribution

Expert Review of Vaccines, 2018
Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported substantial reductions in the incidence of invasive pneumococcal disease (IPD) after implementation of childhood PCV programs.
P. Izurieta, Priti Bahety, R. Adegbola, Christopher Clarke, B. Hoet   +4 more
semanticscholar   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Population-based surveillance for invasive pneumococcal disease in homeless adults in Toronto. [PDF]

PLoS ONE, 2009
BACKGROUND: Identification of high-risk populations for serious infection due to S. pneumoniae will permit appropriately targeted prevention programs. METHODS: We conducted prospective, population-based surveillance for invasive pneumococcal disease and ...
Agron Plevneshi, Tomislav Svoboda, Irene Armstrong, Gregory J Tyrrell, Anna Miranda, Karen Green, Donald Low, Allison McGeer, Toronto Invasive Bacterial Diseases Network   +8 more
doaj   +1 more source

Emerging vaccine strategies against the incessant pneumococcal disease

npj Vaccines, 2023
The incidence of invasive pneumococcal disease (IPD) caused by infection with the pathogen Streptococcus pneumoniae ( Spn ) has been on a downward trend for decades due to worldwide vaccination programs.
J. A. Duke, F. Avci
semanticscholar   +1 more source

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

The remaining challenges of pneumococcal disease in adults [PDF]

European Respiratory Review, 2012
Pneumococcal disease can be divided into invasive disease, i.e. when bacteria are detected in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs more frequently in younger children and older adults.
E. Ludwig, P. Bonanni, G. Rohde, A. Sayiner, A. Torres   +4 more
doaj  

Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis

The Lancet Global Health, 2017
Summary: Background: The full extent to which childhood pneumococcal conjugate vaccines (PCV) can indirectly reduce illness in unvaccinated populations is not known.
Tinevimbo Shiri, DrPhD, Samik Datta, PhD, Jason Madan, PhD, Alexander Tsertsvadze, MD, Pamela Royle, PhD, Matt J Keeling, ProfPhD, Noel D McCarthy, ProfDPhil, Stavros Petrou, ProfPhD   +7 more
doaj   +1 more source

1718. Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: an indirect cohort study [PDF]

, 2023
Kristin L. Andrejko, Ryan Gierke, Jemma V. Rowlands, Jennifer B. Rosen, Ann Thomas, Zachary Landis, María Rosales, Susan Petit, William Schaffner, Corinne Holtzman, Monica M. Farley, Meghan Barnes, Lee H. Harrison, Lesley McGee, Sopio Chochua, Jennifer R. Verani, Adam L. Cohen, Tamara Pilishvili, Miwako Kobyashi   +18 more
openalex   +1 more source