Results 71 to 80 of about 339,808 (204)

Pneumococcal Polysaccharide Vaccination in Pediatric Inflammatory Bowel Disease

Global Pediatric Health, 2019
According to current recommendations, in addition to 13-valent pneumococcal conjugate vaccine (PCV13) series, all children with inflammatory bowel disease (IBD) aged ≥2 years, with planned or current immunosuppression, should receive pneumococcal ...
Tsega Temtem MD, John Whitworth MD, Bindiya Bagga MD   +2 more
doaj   +1 more source

Nasopharyngeal Microbiota in Children With Invasive Pneumococcal Disease: Identification of Bacteria With Potential Disease-Promoting and Protective Effects

Frontiers in Microbiology, 2019
Background and Aims: The risk of suffering from some infectious diseases can be related to specific microbiota profiles. Specifically, the nasopharyngeal microbiota could play a role as a risk or protective factor in the development of invasive disease ...
A. Camelo-Castillo, D. Henares, P. Brotons, A. Galiana, J. C. Rodríguez, A. Mira, C. Muñoz-Almagro   +6 more
semanticscholar   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

Food Frontiers, Volume 6, Issue 6, Page 2554-2574, November 2025.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz, Ayesha Zahid, Hazrat Ismail, Misbah Ajaz   +3 more
wiley   +1 more source

Prevalence and clonal distribution of pcpA, psrP and Pilus-1 among pediatric isolates of Streptococcus pneumoniae. [PDF]

PLoS ONE, 2012
Streptococcus pneumoniae is the leading cause of vaccine-preventable deaths globally. The objective of this study was to determine the distribution and clonal type variability of three potential vaccine antigens: Pneumococcal serine-rich repeat protein ...
Laura Selva, Pilar Ciruela, Krystle Blanchette, Eva del Amo, Roman Pallares, Carlos J Orihuela, Carmen Muñoz-Almagro   +6 more
doaj   +1 more source

The Burden of Hospitalization Due to Klebsiella pneumoniae–Associated Pneumonia in Children Under 5 Years in Low‐ and Middle‐Income Countries: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Introduction Pneumonia is a significant cause of morbidity and mortality in pediatric populations, especially in low‐ and middle‐income countries (LMICs). Knowing the prevalence and role of pathogens in pneumonia cases requiring hospitalization is essential for informing diagnosis, treatment, and prevention approaches.
Alex Odoom, Bismark Opoku‐Asare, Eric S. Donkor   +2 more
wiley   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

EBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield   +8 more
doaj   +1 more source

Comparison of the Impact of Pneumococcal Conjugate Vaccine 10 or Pneumococcal Conjugate Vaccine 13 on Invasive Pneumococcal Disease in Equivalent Populations

Clinical Infectious Diseases, 2017
Background Pneumococccal conjugated pneumococcal vaccine (PCV10) and pneumococcal conjugate vaccine 13 (PCV13), are used in childhood immunization programs worldwide, but direct comparisons of impacts against invasive pneumococcal disease (IPD) in ...
P. Nauclér, I. Galanis, E. Morfeldt, J. Darenberg, Å. Örtqvist, B. Henriques‐Normark   +5 more
semanticscholar   +1 more source

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel, Chaofan Liu, Inga Viktoria Hensel, Jan Van Deun, Raphael Schwendner, Janina Müller‐Deile, Nina Sopel, Andreas Ramming, Mario R. Angeli, Simon Rauber, Cláudia Vilhena, Andreas Baur, Stefan Wirtz, Klaus Überla, Heiko Reutter, Linda‐Marie Mulzer, Alina C. Hilger, Friederike Zunke, Wei Xiang, Gregor Fuhrmann, Claudia Günther   +23 more
wiley   +1 more source

Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk

Occupational and Environmental Medicine, 2019
Objectives Occupational exposures to metal fumes have been associated with increased pneumonia risk, but the risk of invasive pneumococcal disease (IPD) has not been characterised previously.
K. Torén, P. Blanc, R. Naidoo, N. Murgia, I. Qvarfordt, O. Aspevall, A. Dahlman-Hoglund, L. Schioler   +7 more
semanticscholar   +1 more source

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source