Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]
, 2016 Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST +5 more
core +1 more source
Position statement on the management of pregnancy in sickle cell disease
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.Sickle cell disease (SCD) is a hereditary haemoglobinopathy which causes multi‐organ dysfunction. Pregnancies in SCD are high risk with significant maternal and fetal morbidity and mortality, including vaso‐occlusive crises, thrombosis, anaemia, placental insufficiency, fetal growth restriction, preterm birth and medication effects. High level evidence
Mimi Yue +5 more
wiley +1 more source
Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin [PDF]
, 2020 Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not well understood.
Baltazar, Murielle +11 more
core +3 more sources
Identifying spatial invasion of pandemics on metapopulation networks via anatomizing arrival history [PDF]
, 2015 Spatial spread of infectious diseases among populations via the mobility of humans is highly stochastic and heterogeneous. Accurate forecast/mining of the spread process is often hard to be achieved by using statistical or mechanical models. Here we propose a new reverse problem, which aims to identify the stochastically spatial spread process itself ...
arxiv +1 more source
A hybrid gravity and route choice model to assess vector traffic in large-scale road networks [PDF]
R. Soc. open sci. 7: 191858 (2020), 2019 Human traffic along roads can be a major vector for infectious diseases and invasive species. Though most road traffic is local, a small number of long-distance trips can suffice to move an invasion or disease front forward. Therefore, understanding how many agents travel over long distances and which routes they choose is key to successful management ...
arxiv +1 more source
Journal of Clinical Nursing, EarlyView.ABSTRACT Background The infection prevention behaviours of kidney transplant recipients have been investigated, but the factors affecting these have not. Therefore, the present study aimed to examine the infection prevention behaviours of kidney transplant recipients and the factors related to these.
Yaprak Sarıgöl Ordin +1 more
wiley +1 more source
Prevention of pneumococcal diseases in the post-seven valent vaccine era: A European perspective
BMC Infectious Diseases, 2012 Background The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S.
Weil-Olivier Catherine +4 more
doaj +1 more source
Population-based surveillance for invasive pneumococcal disease in homeless adults in Toronto. [PDF]
PLoS ONE, 2009 BACKGROUND: Identification of high-risk populations for serious infection due to S. pneumoniae will permit appropriately targeted prevention programs. METHODS: We conducted prospective, population-based surveillance for invasive pneumococcal disease and ...
Agron Plevneshi +8 more
doaj +1 more source
Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]
, 2012 The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M +10 more
core +1 more source
Mechanisms governing bacterial capsular polysaccharide attachment and chain length
Annals of the New York Academy of Sciences, EarlyView.Abstract Capsular polysaccharides (CPSs) are high‐molecular weight glycopolymers that form a capsule layer on the surface of many bacterial species. This layer serves as a crucial barrier between bacteria and their environment, protecting them from host immune responses and environmental stressors while facilitating adaptation to host niches.
Saroj Khadka +3 more
wiley +1 more source