Invasive pneumococcal disease in relation to vaccine type serotypes
Since 1983 the world has been introduced to four vaccines combating disease caused by Streptococcus pneumoniae bacteria. However, despite vaccination programs disease caused by S.
Paeton L. Wantuch, F. Avci
semanticscholar +1 more source
Updates on Toll‐Like Receptor 10 Research
Toll‐like receptor 10 (TLR10 or CD290) shares the same structural organization as the other TLRs but shows a unique expression pattern and distinct functional activities yet to be fully elucidated. This review summarizes key steps and recent updates on TLR10 research including open questions and future perspectives.
Federica Riva, Marta Muzio
wiley +1 more source
Invasive isolates of Streptococcus pneumoniae in Serbia: Antimicrobial susceptibility and serotypes [PDF]
Introduction. Streptococcus pneumoniae is one of the leading causes of bacterial meningitis and sepsis. Invasive pneumococcal disease is a significant medical problem worldwide, particularly in children, due to a huge increase of pneumococcal ...
Gajić Ina+5 more
doaj +1 more source
Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system. [PDF]
Routine use of pneumococcal conjugate vaccines (PCVs) in developing countries is expected to lead to a significant reduction in childhood deaths. However, PCVs have been associated with replacement disease with non-vaccine serotypes.
Adegbola, Richard A+18 more
core +2 more sources
ABSTRACT This prospective randomized trial examined the impact of extensive lower respiratory tract sampling and microbial analysis on treatment decisions and patient outcomes in community‐acquired pneumonia (CAP). One hundred and eighteen patients were randomized to rigorous sampling (intervention group, n = 64) or standard care (control group, n = 54)
Peter Ellekvist+8 more
wiley +1 more source
The remaining challenges of pneumococcal disease in adults [PDF]
Pneumococcal disease can be divided into invasive disease, i.e. when bacteria are detected in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs more frequently in younger children and older adults.
E. Ludwig+4 more
doaj
Asthma and the Risk of Invasive Pneumococcal Disease: A Meta-analysis
After introduction of PCV, children with asthma continue to have a higher risk of IPD and pneumonia than children without asthma. CONTEXT: Invasive pneumococcal disease (IPD) and pneumonia are a leading cause of morbidity and mortality throughout the ...
J. Castro-Rodriguez, K. Abarca, E. Forno
semanticscholar +1 more source
Hopf-bifurcation analysis of pneumococcal pneumonia with time delays [PDF]
In this paper, a mathematical model of pneumococcal pneumonia with time delays is proposed. The stability theory of delay differential equations is used to analyze the model. The results show that the disease-free equilibrium is asymptotically stable if the control reproduction ratio R0 is less than unity and unstable otherwise.
arxiv
Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana
ABSTRACT Background Adults and adolescents face different barriers to healthcare utilization compared to children. Objective To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31 ...
Kwadwo Faka Gyan+8 more
wiley +1 more source
Pneumococcal Polysaccharide Vaccination in Pediatric Inflammatory Bowel Disease
According to current recommendations, in addition to 13-valent pneumococcal conjugate vaccine (PCV13) series, all children with inflammatory bowel disease (IBD) aged ≥2 years, with planned or current immunosuppression, should receive pneumococcal ...
Tsega Temtem MD+2 more
doaj +1 more source