Results 61 to 70 of about 11,123,027 (272)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The impact of temperature on the life cycle of Gasterophilus pecorum in northwest China

Parasites & Vectors, 2021
Background The departure of the mature larvae of the horse stomach bot fly from the host indicates the beginning of a new infection period. Gasterophilus pecorum is the dominant bot fly species in the desert steppe of the Kalamaili Nature Reserve (KNR ...
Ke Zhang, Heqing Huang, Ran Zhou, Boru Zhang, Chen Wang, Make Ente, Boling Li, Dong Zhang, Kai Li   +8 more
doaj   +1 more source

Invasive Species Terminology: Standardizing for Stakeholder Education

Journal of Extension, 2020
The excessive number of terms associated with invasive species, and their often incorrect usage, hinders stakeholder education about the threats of invasive species.
B. Iannone, Shannon Carnevale, Martin Main, Jeffrey E. Hill, Julie McConnell, Steve A. Johnson, Stephen Enloe, Michael Andreu, Emily Bell, J. Cuda, S. Baker   +10 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessing the invasive risk of Procambarus virginalis (marbled crayfish) in South Korea

Journal of Ecology and Environment
Background: Introducing invasive alien species can reduce biodiversity by interfering with native species or spreading disease and having socioeconomic consequences.
Hyungsoon Jeong, Ju Hui Choi
doaj   +1 more source

Drug efficacy of ivermectin against primary nematodes parasitizing captive Przewalski’s horse (Equus ferus przewalskii) after ten years of annually treatment

Helminthologia, 2020
Reintroduction of endangered species to natural habitat is considered as an important tool for conservation. The effect of drug management on captive population of reintroduced species is largely neglected.
Tang L., Xiu Y., Yan L., Cui Y., Ma X., Ente M., Zhang Y., Li K., Zhang D.   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Too hot, too tough, too crowded: Abiotic and biotic constraints on Niphograpta albiguttalis establishment on water hyacinth (Pontederia crassipes) in the southeastern United States

Biological Control
The water hyacinth moth Niphograpta albiguttalis was introduced from Argentina to the United States in the 1970s for the biological control of water hyacinth.
F. Mariani, E.G. Steen, B.G. Rector, P.D. Pratt, R. Diaz   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source