Results 21 to 30 of about 141,544 (250)

Conscious prone positioning during non-invasive ventilation in COVID-19 patients: experience from a single centre [version 1; peer review: 2 approved]

F1000Research, 2020
Critically ill patients admitted to hospital following SARS-CoV-2 infection often experience hypoxic respiratory failure and a proportion require invasive mechanical ventilation to maintain adequate oxygenation.
Helmi C. Burton-Papp, Alexander I. R. Jackson, Ryan Beecham, Matteo Ferrari, Myra Nasim-Mohi, Michael P. W. Grocott, Robert Chambers, Ahilanandan Dushianthan, University Hospital Southampton Critical Care Team, REACT COVID Investigators   +9 more
doaj   +1 more source

What is optimal in patients with myasthenic crisis: Invasive or non-invasive ventilation?

Journal of Neuroanaesthesiology and Critical Care, 2014
Myasthenia gravis is an immune disorder involving the neuromuscular junction. The consequent weakness of respiratory muscles leads to variable disorders of ventilation in patients with myasthenia gravis.
Hemant Bhagat, Vinod K. Grover, Kiran Jangra   +2 more
doaj   +1 more source

Association Between Acute Kidney Injury During Invasive Mechanical Ventilation and ICU Outcomes and Respiratory System Mechanics

Critical Care Explorations, 2022
OBJECTIVES:. Compare ICU outcomes and respiratory system mechanics in patients with and without acute kidney injury during invasive mechanical ventilation. DESIGNS:. Retrospective cohort study. SETTINGS:.
Sneha V. Vemuri, MBChB, Mark L. Rolfsen, MD, Alexandra V. Sykes, MD, Puja G. Takiar, MD, Austin J. Leonard, BA, Atul Malhotra, MD, Roger G. Spragg, MD, Etienne Macedo, MD, PhD, Mark L. Hepokoski, MD   +8 more
doaj   +1 more source

Prospective Validation and Usability Evaluation of a Mobile Diagnostic App for Obstructive Sleep Apnea

Diagnostics
Background/Objectives: Obstructive sleep apnea (OSA) classification relies on polysomnography (PSG) results. Current guidelines recommend the development of clinical prediction algorithms in screening prior to PSG.
Pedro Amorim, Daniela Ferreira-Santos, Marta Drummond, Pedro Pereira Rodrigues   +3 more
doaj   +1 more source

Required biological time for lung maturation and duration of invasive ventilation: a Korean cohort study of very low birth weight infants

Frontiers in Pediatrics, 2023
BackgroundWe investigated the duration of invasive ventilation among very low birth weight (VLBW) infants to evaluate the current minimum time required for lung maturation to breathe without ventilator assistance after preterm birth.MethodsA total of 14 ...
Heui Seung Jo, Myoung Nam Lim, Sung-Il Cho   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Clinical Study of Different Modes of Non-invasive Ventilation Treatment in Preterm Infants With Respiratory Distress Syndrome After Extubation

Frontiers in Pediatrics, 2020
Objective: This study aimed to investigate the clinical efficacy and safety of different non-invasive respiratory support methods in preterm infants with respiratory distress syndrome (RDS) after extubation.Methods: From Oct 2017 to 2018, 120 preterm ...
Fei Ding, Jingling Zhang, Wenya Zhang, Qian Zhao, Zimei Cheng, Yang Wang, Tao Bo, Hui Wu   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Non-invasive Ventilation and CPAP Failure in Children and Indications for Invasive Ventilation

Frontiers in Pediatrics, 2020
Non-invasive ventilation (NIV) and continuous positive airway pressure (CPAP) are effective treatments for children with severe sleep disordered breathing (SBD).
Alessandro Amaddeo, Alessandro Amaddeo, Sonia Khirani, Sonia Khirani, Sonia Khirani, Lucie Griffon, Lucie Griffon, Theo Teng, Agathe Lanzeray, Brigitte Fauroux, Brigitte Fauroux   +10 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source