Results 121 to 130 of about 788,664 (335)

Invention in Philippine Industry [PDF]

open access: yes
This paper is presented at the Third National Convention on Statistics at the Philippine International Convention Center on December 13-14, 1982. It discusses the different legal instruments utilized in the Philippines to encourage invention and to ...
Evenson, Robert E.   +2 more
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Corrigendum: The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Ziyu Zhang   +8 more
doaj   +1 more source

Understanding the Doctrine of Patentable Subject Matter [PDF]

open access: yes, 2010
The doctrine of patentable subject matter precludes basic inventions such as abstract ideas and laws of nature from patent protection. However, current economic thinking of the patent systemstresses the necessity of rewarding pioneering inventors in ...
Chiou, Jing-Yuan
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A Reconsideration of the Physicians’ Immunity Statute [PDF]

open access: yes, 2001
The author assesses the physicians\u27 immunity statute from legal policy, ethical, and financial perspectives, and concludes that alternatives such as licensure and monetary incentives would better serve the goal of encouraging invention more ...
Dirksen, Steve
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

[Review of] Werner Sollors, cd. The Invention of Ethnicity [PDF]

open access: yes, 1992
The Invention of Ethnicity is obviously and admittedly shaped after Hobsbawm\u27s and Ranger\u27s Invention of Tradition, published in 1986, when the essays in this volume were finished. In the meantime, much of what Sollors argues for in his editor\u27s
Isernhagen, Hartwig
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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