Results 141 to 150 of about 196,083 (317)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Küresel bilgi ekonomisinde keskin rekabet ortamıhem kamu sektörünü hem de aynızamanda özel sektörü olağanüstü biçimde etkilemektedir. İşletmeler çalkantılırekabet ortamında daha çok pazar payıelde etme yarışının bir sonucu olarak sürekli yeni ürünler ...
Adem Öğüt +3 more
doaj
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Energy Saving Through Development of New Copper Rotor of Induction Motor
Prof. Dr. Ismail Daut and his team won silver at 21st International Invention, Innovation and Technology Exhibition (ITEX) 2010, 14th - 16th May 2010 di Kuala Lumpur Convention Centre (KLCC), Kuala Lumpur, Malaysia.This product describes the importance ...
Anayet, Karim +5 more
core
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Concrete Ceramic Waste Slab (CCWS)
Mohd Mustafa Al Bakri Abdullah and his team won bronze for Concrete Ceramic Waste Slab (CCWS) at 17th International Invention, Innovation & Technology Exhibition 2006 (ITEX 2006), 19th - 21st May 2006 at Kuala Lumpur Convention Centre (KLCC), Kuala ...
Shamsul Baharin, Jamaludin, Prof. Madya +3 more
core

