Results 141 to 150 of about 196,083 (317)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

İŞLETMELERDE DÜŞÜNCE AŞAMASINDAN PATENT AŞAMASINA UZANAN SÜREÇTE YENİLİK STRATEJİLERİVE BULUŞ YÖNETİMİ

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2007
Küresel bilgi ekonomisinde keskin rekabet ortamıhem kamu sektörünü hem de aynızamanda özel sektörü olağanüstü biçimde etkilemektedir. İşletmeler çalkantılırekabet ortamında daha çok pazar payıelde etme yarışının bir sonucu olarak sürekli yeni ürünler ...
Adem Öğüt   +3 more
doaj  

Invention and "Invention" [PDF]

open access: yesMeta: Journal des traducteurs, 1978
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Energy Saving Through Development of New Copper Rotor of Induction Motor

open access: yes, 2010
Prof. Dr. Ismail Daut and his team won silver at 21st International Invention, Innovation and Technology Exhibition (ITEX) 2010, 14th - 16th May 2010 di Kuala Lumpur Convention Centre (KLCC), Kuala Lumpur, Malaysia.This product describes the importance ...
Anayet, Karim   +5 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Concrete Ceramic Waste Slab (CCWS)

open access: yes, 2006
Mohd Mustafa Al Bakri Abdullah and his team won bronze for Concrete Ceramic Waste Slab (CCWS) at 17th International Invention, Innovation & Technology Exhibition 2006 (ITEX 2006), 19th - 21st May 2006 at Kuala Lumpur Convention Centre (KLCC), Kuala ...
Shamsul Baharin, Jamaludin, Prof. Madya   +3 more
core  

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