Results 121 to 130 of about 196,083 (317)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Scientific Annals of Economics and BusinessInnovation currently represents a significant source of added value and competitiveness for companies on the international scale. However, financing innovation activities is a real challenge to overcome in order to successfully achieve the goals in ...
Mohamed Oudgou, Abdeslam Boudhar
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The independent invention defence in a Cournot duopoly model [PDF]
Maurer and Scotchmer (2002) pointed out that patents may be inferior to other forms of intellectual property in that the independent invention is not a defence to infringement.
Elisabetta Ottoz, Franco Cugno
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Serious Game : invention humaine ou d’animaux ?
L’objectif de cet article est de questionner si le Serious Game correspond à une invention humaine. Pour répondre à une telle interrogation, nous proposons de vérifier si du jeu sérieux peut être recensée dans le règne animal.
Julian Alvarez
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
, 2012 Dr. Haftirman and his team from School of Mechatronic Engineering won gold for Micro fatigue testing machine. 23rd International Invention, Innovation and Technology Exhibition 2012 (ITEX 2012) organized by Malaysian Invention and Design Society (MINDS),
Haftirman, Dr. +1 more
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