Results 61 to 70 of about 86,889 (293)
General Purpose Alarm Device: A programmable annunciator
HardwareXThe General Purpose Alarm Device (GPAD) shines lights and makes loud noises to draw the attention of a human being to a problem. It provides a programmable, 80 character display to provide textual information. As an inexpensive modular annunciator, it is
Robert L. Read +2 more
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Journal of Intellectual PropertySupreme Court decision 2017Hu1304 has established an inherency doctrine in determining novelty. According to the decision, it is not enough to simply show the possibility or probability that something can be done to show prior art to be the same as the ...
Joohwan Lee
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Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Reference Genes for Expression Analyses by qRT-PCR in Enterobacter cancerogenus
MicroorganismsThe Enterobacter cancerogenus strain EcHa1 was isolated from the dead larvae of Helicoverpa armigera, and has the potential for biocontrol of some Lepidoptera insects.
Yang Pan +7 more
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Invention as a Link in Scientific and Economic Progress1 [PDF]
, 1927 James Henderson
openalex +3 more sources
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A potential biomarker of isofenphos-methyl in humans: A chiral view
Environment International, 2019 Isofenphos-methyl (IFP) is a very active and persistent chiral insecticide. However, IFP has lower activity against acetylcholinesterases (AChEs). Previously, it was confirmed that phosphorothioate organophosphorus pesticides with N-alkyl (POPN) require ...
Beibei Gao +9 more
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