Results 61 to 70 of about 52,817 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis and Evaluation of the Patent Court Decision 2023na11276, October 31, 2024, Regarding the Enhanced Damages under the Patent Act

open access: yesJournal of Intellectual Property
Because the enhanced damages under the Patent Act went into effect on July 9, 2019, no decision was made to calculate enhanced damages until the Busan District Court 2023GaHap42160 decision because the lower courts had previously decided that if patent ...
Joohwan Lee
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On the economical politics of invention [PDF]

open access: yesFilozofija i Društvo
This article tackles the question of invention in Jacques Derrida’s thought of deconstruction according to two perspectives. In the first part, draw­ing on “Psyché: Invention of the Other”, it examines its economic impli­cations; in the second ...
De Michele Giustino
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Invention of Leshy

open access: yesGames and Culture
The objective of this paper is to examine the role of a digital game series in elevating this relatively minor mythological figure to the status of a synecdoche for the broader concept of “Slavic mythology” and in its appropriation as part of Polish cultural heritage. To this end, this study analyzes Leshy's position in both Polish
Tomasz Z. Majkowski   +2 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Fluorescent probes for imaging and detection of plant hormones and their receptors

open access: yesAdvanced Agrochem
Exploring plant behavior at the cellular scale in a minimally invasive manner is critical to understanding plant adaptation to the environment. Phytohormones play vital regulatory roles in multiple aspects of plant growth and development and acclimation ...
Yiliang Chen   +6 more
doaj   +1 more source

L’invention de l’« enthousiasme » poétique

open access: yesCahiers Mondes Anciens, 2018
For archaic and classical Greek authors, poetic creation as a process associates divine inspiration, which implies near communication with superior entities such as the Muses, and crafty technique.
Michel Briand
doaj   +1 more source

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