Results 141 to 150 of about 52,986 (288)

Contributing to Markets for Technology? A Comparison of Patent Filing Motives of Individual Inventors, Small Companies and Universities

, 2011
Theresa Veer, Florian Jell
openalex   +1 more source

Vivian Richard Ebsary, A.M. Biomedical Engineer, Inventor, Philanthropist [PDF]

, 2005
Helen O’Brien
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Overcoming Normalcy Bias in Acute Myocardial Infarction: A Case Report of Generative AI as a Behavioral Catalyst for Emergency Care Seeking. [PDF]

Cureus
Ikeda O, Oyamada N, Hayashi M.
europepmc   +1 more source

Must an Inventor "Possess" an Invention to Patent It? [PDF]

, 2014
Warren D Woessner, Robin A Chadwick
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Public impression of an innovative stair-climbing power wheelchair: A pilot survey

Hong Kong Physiotherapy Journal, 2015
S.L. Li, Grad. Dip. Adv. Manip. Ther, A. Lee   +1 more
doaj   +1 more source

Changes in Oxygen Metabolism Biomarkers of Ischemic Tissue Treated With Electrical Stimulation. [PDF]

Stroke Vasc Interv Neurol
Bahr-Hosseini M, Asghariahmadabad M, Bikson M, Saver JL, Liebeskind DS, Nael K.   +5 more
europepmc   +1 more source

A helping hand for inventors [PDF]

, 1987
Bill Johnstone
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source