Results 41 to 50 of about 93,257 (315)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Aerosol deposition and origin in French mountains estimated with soil inventories of 210Pb and artificial radionuclides [PDF]
, 2008 Radionuclide inventories were measured in soils from different French mountainous areas: Chaîne des Puys (Massif Central), Eastern Corsica, Jura, Montagne Noire, Savoie, Vosges and Rhine Valley. 210Pb soil inventories were used to estimate long-term (>75
Le Roux, Gaël +5 more
core +1 more source
Input and Output Inventories in the UK [PDF]
What is the role of inventories in UK manufacturing? We present and estimate a model of inventories that considers separately finished goods and input (i.e. the sum of raw materials and work-in-process) inventories.
Tsoukalas, John
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Sociedade & Natureza, 2021 This study aimed to assess landslide susceptibility in the Sahla watershed in northern Morocco. Landslides hazard is the most frequent phenomenon in this part of the state due to its mountainous precarious environment.
Abdelhak El-Fengour +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Comparison and Assessment of Two Emission inventories for the Madrid Region
, 2011 Emission inventories are databases that aim to describe the polluting activities that occur across a certain geographic domain. According to the spatial scale, the availability of information will vary as well as the applied assumptions, which will ...
Borge García, Rafael +4 more
core +1 more source
Environmental Research Letters, 2017 Greenhouse gas and air pollutant precursor emissions have been increasing rapidly in India. Large uncertainties exist in emissions inventories and quantification of their uncertainties is essential for better understanding of the linkages among emissions
Eri Saikawa +10 more
doaj +1 more source