Results 81 to 90 of about 121,760 (314)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

EVELOPMENT OF THE SCOR MODEL IN THE EFFICIENCY OF AGROINDUSTRY INVENTORY MANAGEMENT: CASE STUDY OF THE AGROINDUSTRY LYOPHILIZER COMPANY, AREQUIPA [PDF]

Proceedings on Engineering Sciences
This study implements the SCOR Model (Supply Chain Operations Reference) to optimize inventory management in a freeze-drying agro-industrial company in Arequipa, Peru.
Aylen Ayme Choque Llerena , Alexis Paul Salinas Rojas , Jose Alberto Aguilar Franco , Carmen Mariaelena Villanuena Delgado , Marcia Shantal Caipo Huacasi   +4 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Research into the features of organising and controlling two-tier inventory management systems under demand variability

Цифровые модели и решения
The article deals with the issue of modelling the dynamics of random processes arising in the planning of an inventory management system. The study aims to analyse the capabilities of the mathematical apparatus of queuing theory in inventory management ...
Irina N. Bulgakova, Sofya Yu. Sviridova
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

The French Section of the Este Library in the 15th Century: Sedimentation, Evolution and Dispersion. The Case of Arthurian Novels

TECA, 2013
The research examines, through the analysis of the documents, the history of the French codices which made up one of the largest and most important sections in the bibliotheca publica of the Este family.
Armando Antonelli
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Inventories and the Business Cycle [PDF]

This paper examines the relationship between the inventory cycle and the business cycle. It uses both macro-economic data and data from surveys of individual firms’ actual and expected inventory accumulation.
Darren Flood, Philip Lowe
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Spatial–Temporal Variations in Soil Organic Carbon and Driving Factors in Guangdong, China (2009–2023)

Land
Spatial–temporal variation in soil organic carbon is an important factor for national targets to mitigate climate change and land degradation impacts. In this research, we took Guangdong Province of China as the study area, evaluated the spatial–temporal
Mi Tian, Chao Wu, Xin Zhu, Qinghai Hu, Xueqiu Wang, Binbin Sun, Jian Zhou, Wei Wang, Qinghua Chi, Hanliang Liu, Yuheng Liu, Jiwu Yang, Xurong Li   +12 more
doaj   +1 more source