Results 81 to 90 of about 275,657 (308)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Metamodelling of Inventory-Control Simulations Based on a Multilayer Perceptron

open access: yesTransport and Telecommunication, 2019
Inventory control problems arise in various industries, and each single real-world inventory is replete with non-standard factors and subtleties. Practical stochastic inventory control problems are often analytically intractable, because of their ...
Jackson Ilya   +3 more
doaj   +1 more source

PENGEMBANGAN SISTEM PENDUKUNG KEPUTUSAN PENGENDALIAN PERSEDIAAN BARANG MENGGUNAKAN METODE ECONOMIC ORDER QUANTITY (EOQ) DAN MIN-MAX BERBASIS WEB (STUDI KASUS : APOTEK SAHABAT QITA)

open access: yesJurnal Nasional Pendidikan Teknik Informatika (JANAPATI), 2019
Inventory control is very important because the shortage or excess inventory is a factor that triggers an increase in cost. Excess inventory will make the cost incurred to be greater and risk of damage or expiration, whereas if a small inventory of goods
Gde Gung Prabawa   +2 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Satisficing Newsvendor Problem with the Optimism Coefficient

open access: yesFoundations of Computing and Decision Sciences, 2019
In this research note the satisficing newsvendor problem is considered which is defined as the maximization of the probability of exceeding the expected profit multiplied by a positive constant.
Bieniek Milena
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Recent evidence on the muted inventory cycle [PDF]

open access: yes
Inventories play an important role in business cycles. Inventory build-ups add momentum to the economy during expansions, while inventory liquidations sap economic strength during recessions.
Andrew J. Filardo
core  

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