Results 71 to 80 of about 296,829 (338)

Using Branch-and-Price to Find High Quality Solutions Quickly [PDF]

open access: yes, 2009
We develop an exact solution approach for integer programs that produces high- quality solutions quickly by solving well-chosen restrictions of the problem.
Hewitt, Mike   +2 more
core   +1 more source

Time-Dependent Travel-Time Constrained Inventory Routing Problem [PDF]

open access: yes, 2020
The Inventory Routing Problem (IRP) is an integration of two operational problems: inventory management and routing. The Time-Dependent Travel-Time Constrained (TD-TC-IRP) is a new proposed variant of the IRP where the travelling time between two locations depend on the time of departure throughout the day and the length of a trip is time-constrained ...
Touzout, Faycal   +2 more
openaire   +2 more sources

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

The Online Distribution System of Inventory-Routing Problem with Simultaneous Deliveries and Returns Concerning CO2 Emission Cost

open access: yesMathematics, 2020
This study attempts to consider CO2 emission cost to propose an online distribution system of inventory-routing problem with simultaneous deliveries and returns (IRPSDRCO2).
Gia-Shie Liu, Kuo-Ping Lin
doaj   +1 more source

An integrated model for cash transfer system design problem [PDF]

open access: yes, 2013
This paper presents an integrated model that incorporates strategic, tactical, and operational decisions for a cash transfer management system of a bank.
Dasci, Abdullah   +4 more
core  

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

open access: yesAdvanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi   +15 more
wiley   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li   +8 more
wiley   +1 more source

A Library Review Study: Conceptual Model for Maritime Inventory-Routing Problem [PDF]

open access: yesInternational Journal of Supply and Operations Management, 2017
The main focus of this paper is presenting a conceptual structure for Maritime Inventory-Routing Problem. We have looked at the matter from the supply chain angel and summed up the main comprising elements and major hypotheses in the framework of a ...
Ali Nazemi   +2 more
doaj   +1 more source

Optimisation of a distribution system in the retail industry: An Australian retail industry [PDF]

open access: yes, 2019
This paper develops a mathematical model based on inventory routing problem that aims to minimise transportation cost, inventory carrying cost and optimises delivery schedules in a retail Australian industry.
Amjad, M., Daniel, J., Garza-Reyes, J.A.
core   +1 more source

A dynamic approach to rebalancing bike-sharing systems [PDF]

open access: yes, 2018
Bike-sharing services are flourishing in Smart Cities worldwide. They provide a low-cost and environment-friendly transportation alternative and help reduce traffic congestion.
Chiariotti, Federico   +3 more
core   +3 more sources

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