Results 61 to 70 of about 1,391,068 (260)

Nonlinear nanophotonic devices in the ultraviolet to visible wavelength range

Nanophotonics, 2020
Although the first lasers invented operated in the visible, the first on-chip devices were optimized for near-infrared (IR) performance driven by demand in telecommunications.
He Jinghan, Chen Hong, Hu Jin, Zhou Jingan, Zhang Yingmu, Kovach Andre, Sideris Constantine, Harrison Mark C., Zhao Yuji, Armani Andrea M.   +9 more
doaj   +1 more source

Deep learning for topological photonics

Advances in Physics: X, 2022
In this paper, we review the specific field that combines topological photonics and deep learning (DL). Recent progress of topological photonics has attracted enormous interest for its novel and exotic properties such as unidirectional propagation of ...
Jooyeong Yun, Seokwoo Kim, Sunae So, Minkyung Kim, Junsuk Rho   +4 more
doaj   +1 more source

Collision-free inverse kinematics of the redundant seven-link manipulator used in a cucumber picking robot

, 2010
The paper presents results of research on an inverse kinematics algorithm that has been used in a functional model of a cucumber-harvesting robot consisting of a redundant P6R manipulator.
Barreiro Elorza, Pilar, Meuleman, J., Schenk, E.J., Van Henten, E.J., Van Willigenburg, L.G.   +4 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Inverse design of polaritonic devices

Applied Physics Letters
Polaritons, arising from the strong coupling between excitons and photons within microcavities, hold promise for optoelectronic and all-optical devices. They have found applications in various domains, including low-threshold lasers and quantum information processing. To realize complex functionalities, non-intuitive designs for polaritonic devices are
Oliver Kuster, Yannick Augenstein, Carsten Rockstuhl, Thomas Jebb Sturges   +3 more
openaire   +4 more sources

Fussy Inverse Design of Metamaterial Absorbers Assisted by a Generative Adversarial Network

Frontiers in Materials, 2022
The increasing demands for metasurfaces have led researchers to seek effective inverse design methods, which are counting on the developments in the optimization theory and deep learning techniques.
Hai Lin, Yuze Tian, Junjie Hou, Weilin Xu, Xinyang Shi, Rongxin Tang   +5 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Design method for quasi-isotropic transformation materials based on inverse Laplace's equation with sliding boundaries

, 2010
The deformation method of transformation optics has been demonstrated to be a useful tool, especially in designing arbitrary and nonsingular transformation materials.
Gabrielli, Gengkai Hu, Genov, Hu, Hu, Hu, Jiang, Jin Hu, Kallos, Kwon, Lai, Landy, Leonhardt, Leonhardt, Li, Li, Liu, Ma, Nicolet, Pendry, Rahm, Schurig, Valentine, Xiaoming Zhou, You, Zhang, Zheng Chang   +26 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

AlphaFold distillation for inverse protein design

Scientific Reports
Inverse protein folding, the process of designing sequences that fold into a specific 3D structure, is crucial in bio-engineering and drug discovery. Traditional methods rely on experimentally resolved structures, but these cover only a small fraction of
Igor Melnyk, Aurélie Lozano, Payel Das, Vijil Chenthamarakshan   +3 more
doaj   +1 more source