Results 61 to 70 of about 1,401,348 (279)

Designing Illumination Lenses and Mirrors by the Numerical Solution of Monge-Amp\`ere Equations

, 2015
We consider the inverse refractor and the inverse reflector problem. The task is to design a free-form lens or a free-form mirror that, when illuminated by a point light source, produces a given illumination pattern on a target.
Brix, Kolja, Hafizogullari, Yasemin, Platen, Andreas   +2 more
core   +1 more source

Inverse design of photonic crystal devices [PDF]

IEEE Journal on Selected Areas in Communications, 2005
This work deals with the inverse design in the field of photonic crystal based devices. Here an inverse method containing a fast and accurate simulation method integrated with a competent optimization method is presented. Two designs yielded from this conjunction of multiple scattering theory with a genetic algorithm is analyzed.
Hakansson, Andreas, Sanchez-Dehesa, Jose, Sanchis, Lorenzo   +2 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Fine-Tuning of Nonlinear Optical Contrasts of Hexaphyrin-Based Molecular Switches Using Inverse Design

Frontiers in Chemistry, 2021
In the search for new nonlinear optical (NLO) switching devices, expanded porphyrins have emerged as ideal candidates thanks to their tunable chemical and photophysical properties.
Eline Desmedt, Tatiana Woller, Jos L. Teunissen, Freija De Vleeschouwer, Mercedes Alonso   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A Multi-Category Inverse Design Neural Network and Its Application to Diblock Copolymers

Mathematics, 2022
In this work, we design a multi-category inverse design neural network to map ordered periodic structures to physical parameters. The neural network model consists of two parts, a classifier and Structure-Parameter-Mapping (SPM) subnets.
Dan Wei, Tiejun Zhou, Yunqing Huang, Kai Jiang   +3 more
doaj   +1 more source

Inverse design of polaritonic devices

Applied Physics Letters
Polaritons, arising from the strong coupling between excitons and photons within microcavities, hold promise for optoelectronic and all-optical devices. They have found applications in various domains, including low-threshold lasers and quantum information processing. To realize complex functionalities, non-intuitive designs for polaritonic devices are
Oliver Kuster, Yannick Augenstein, Carsten Rockstuhl, Thomas Jebb Sturges   +3 more
openaire   +4 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Inverse design of anisotropic bone scaffold based on machine learning and regenerative genetic algorithm

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Triply periodic minimal surface (TPMS) is widely used in the design of bone scaffolds due to its structural advantages. However, the current approach to designing bone scaffolds using TPMS structures is limited to a forward process from ...
Wenhang Liu, Youwei Zhang, Yongtao Lyu, Yongtao Lyu, Sergei Bosiakov, Yadong Liu   +5 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source