Bridging binarization: causal inference with dichotomized continuous exposures. [PDF]
Lee K, Hubbard A, Schuler A.
europepmc +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
AGL-UNet: Adaptive Global-Local Modulated U-Net for Multitask Sea Ice Mapping. [PDF]
Chen D, Zheng F.
europepmc +1 more source
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu +12 more
wiley +1 more source
The causal relationship between atopic dermatitis and retinal detachment: A 2-sample Mendelian randomization analysis. [PDF]
Liu X, Li H, Tang T, Zhu Y, Zhu S.
europepmc +1 more source
Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio +3 more
wiley +1 more source
The causal relationship between cathepsins and ankylosing spondylitis: a two-sample Mendelian randomization study. [PDF]
Wu B +7 more
europepmc +1 more source
Solid Harmonic Wavelet Bispectrum for Image Analysis
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
Case-mix adjustment through inverse probability weighting to compare health indicators across territories or providers - an application in the agency for health protection of Milan. [PDF]
Mazzali C +7 more
europepmc +1 more source
Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu +9 more
wiley +1 more source

