Results 51 to 60 of about 3,374 (214)

A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces

open access: yesAdvanced Science, EarlyView.
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren   +5 more
wiley   +1 more source

Design and Stability Analysis Techniques for Switching-Mode Nonlinear Circuits: Power Amplifiers and Oscillators [PDF]

open access: yes, 2006
A design technique for kW level switching mode power amplifiers is presented. Several push pull pairs, independently tuned to Class E/Fodd, are combined by a distributed active transformer.
Jeon, Sanggeun
core   +1 more source

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

open access: yesAdvanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao   +19 more
wiley   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

open access: yesAdvanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu   +5 more
wiley   +1 more source

Logic programming and partial deduction for the verification of reactive systems: An experimental evaluation

open access: yes, 2002
In earlier work it has been shown that finite state CTL model checking of reactive systems can be achieved by a relatively simple interpreter written in tabled logic programming.
Massart, Thierry, Leuschel, Michael
core  

Tackling the Inverse Problem for Non-Autonomous Systems: Application to the Life Sciences. [PDF]

open access: yes, 2012
The common assumption that a dynamical system found in nature can be considered as isolated and autonomous is frequently a poor approximation. In reality, there are always external influences, and these are often too strong to ignore.
Stankovski, Tomislav
core  

Modulating anxiety with extrasynaptic inhibition [PDF]

open access: yes, 2014
Traumatic experiences and stress can lead to complex behavioral adaptations, including increased levels of anxiety and fear generalization. The neuronal mechanisms underlying such maladaptive behavioral changes are, however, poorly understood.
Botta, Paolo
core   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks

open access: yes, 2021
Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the \(G_{i/o}\) pathway and illumination with blue/green light inactivates G protein-coupled inwardly ...
Herlitze, Stefan (Prof. Dr. rer. nat.)   +10 more
core  

Turbulence in the interstellar medium [PDF]

open access: yes, 2014
Turbulence is ubiquitous in the insterstellar medium and plays a major role in several processes such as the formation of dense structures and stars, the stability of molecular clouds, the amplification of magnetic fields, and the re-acceleration and ...
Chian, A. C. -L.   +9 more
core   +1 more source

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