Results 61 to 70 of about 24,583 (261)

Verification of the Semiquantitative Assessment of Vertebral Deformity for Subsequent Vertebral Body Fracture Prediction and Screening for the Initiation of Osteoporosis Treatment: A Case-Control Study Using a Clinical-Based Setting

open access: yesOsteology
Background/Objectives: Semiquantitative grading of the vertebral body (SQ) is an easy screening method for vertebral body deformation. The validity of SQ as a risk factor and screening tool for incident osteoporotic fractures in the vertebral body (OF ...
Ichiro Yoshii   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Experimental Investigation, The Effect of Shape of slots on the bridge scour of pier( the comparison of diamond and square) [PDF]

open access: yesمهندسی منابع آب, 2019
One of the scour-control methods around the bridge's pier is use a slot. In the present study the effect of the shape of slot, on local scour around bridge piers have been studied.
مرتضی بختیاری   +3 more
doaj  

Effect of impairement in left ventricular filling pressure on exercise tolerance in patients with chronic obstructive pulmonary disease

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2019
Background Chronic obstructive pulmonary disease (COPD) is a progressive irreversible obstruction in the airways that could be preventable. It has some significant extrapulmonary adverse effects that add to severity of the disease.
Aya D.M Abdel   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

CT angiography collateral scoring: Correlation with DWI infarct size in proximal middle cerebral artery occlusion stroke within 12 h onset

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2016
Purpose: It had been postulated that intra-cranial collateral flow can maintain penumbra and limit infarct growth in acute stroke patients. CT angiography is a frequently performed non-invasive modality for evaluation of intracranial collaterals. In this
Mahmoud M. Higazi, Enas A. Abdel-Gawad
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

A study based on stress-strain transfer ratio calculation using Halpin-Tsai and MROM material model for limit elastic analysis of metal matrix FG rotating disk [PDF]

open access: yesFME Transactions, 2020
Limit elastic analysis of a functionally graded (FG) rotating disk with material grading based on modified rule of mixture (MROM) is reported in the present study.
Madan Royal   +2 more
doaj  

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