Results 41 to 50 of about 3,228,264 (291)
Identification of raloxifene as a novel CB2 inverse agonist [PDF]
The purpose of the current study was to apply a high throughput assay to systematically screen a library of food and drug administration (FDA)-approved drugs as potential ligands for the cannabinoid receptor 2 (CB2). A cell-based, homogenous time resolved fluorescence (HTRF) method for measuring changes in intracellular cAMP levels was validated and ...
Pritesh, Kumar, Zhao-Hui, Song
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Large-scale inverse problems that require high-performance computing arise in various fields, including regional air quality studies. The paper focuses on parallel solutions of an emission source identification problem for a 2D advection–diffusion ...
Alexey Penenko, Evgeny Rusin
doaj +1 more source
Feedback methods for inverse simulation of dynamic models for engineering systems applications [PDF]
Inverse simulation is a form of inverse modelling in which computer simulation methods are used to find the time histories of input variables that, for a given model, match a set of required output responses.
David J. Murray-Smith +1 more
core +1 more source
Contact-induced mistuning at the blade–disk interface is a major source of variability in the dynamic response of bladed disks, yet its identification remains challenging due to the intrinsic complexity of the contact phenomenon.
Umidjon Usmanov +2 more
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The accurate dynamic model of the chemical process is an important condition for the successful implementation of advanced control in the plant. In this paper, an efficient second order algorithm for long short-term memory (LSTM) network training is ...
Yaxin Wang, Baochang Xu
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An inverse Stefan problem: identification of boundary value
A spatially one-dimensional inverse Stefan problem is considered: the moving boundary (its evolution in time) is given, the temporal evolution of the temperature at the non-moving boundary is to be determined. The standard integral equation of first kind for this problem is transformed into an equivalent convolution equation.
Ang, D.D. +2 more
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Inverse load identification in vibrating nanoplates
In this paper, we consider the uniqueness issue for the inverse problem of load identification in a nanoplate by dynamic measurements. Working in the framework of the strain gradient linear elasticity theory, we first deduce a Kirchhoff‐Love nanoplate model, and we analyze the well‐posedness of the equilibrium problem, clarifying the correct Neumann ...
Kawano A., Morassi A., Zaera R.
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Standard compatibility-based truss models, including the Disturbed Stress Field Model (DSFM), often underestimate the shear strength and deformation capacity of reinforced-concrete (RC) beam-column joints.
Mehmet Ozan Yılmaz
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ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source

