Results 61 to 70 of about 3,228,264 (291)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Identification and an Inverse Filtering Problem
IFAC-PapersOnLine, 2018 Abstract This paper is devoted to the problem of compensating for errors of nonlinear dynamical systems (DSs) between observation sessions. Such a problem is connected with the coordination of solutions of the nonlinear differential equations for the DSs and the linearized equations for their errors.
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2017 This paper proposes identification method of excitation force of rigid body vibration source by physical model identification. If the reworking occurs after the assembly of the prototype in mechanical product, the cost increases due to the retrofit ...
Takahiro SHINOZAKI, Koichi HONKE
doaj +1 more source
Direct Bayesian Identification of Inverse Linear Systems
IEEE Control Systems LettersThe kernel-based inverse system identification framework enables accurate identification of systems with non-minimum phase dynamics, greatly expanding the potential of non-causal system identification approaches. The existing kernel-based inverse system identification method performs the estimation assuming noisy input data, while in practice noise is ...
Rikuto Suzuki +2 more
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Inverse problem for coefficient identification in the Euler–Bernoulli equation
Computers & Mathematics with Applications, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tchavdar T. Marinov, Aghalaya S. Vatsala
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Journal of Advances in Modeling Earth Systems, 2021 Geophysical models make predictions relying on parameter values to be estimated from data. However, existing methods are costly because they require either many runs of the complex geophysical model or to implement an adjoint model.
Clement Aldebert +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
An holomorphic study of Smarandache automorphic and cross inverse property loops [PDF]
, 2008 By studying the holomorphic structure of automorphic inverse property uasigroups and loops[AIPQ and (AIPL)] and cross inverse property quasigroups and loops[CIPQ and (CIPL)], it is established that the holomorph of a loop is a Smarandache; AIPL, CIPL, K ...
Gbolahan, Temitoe +1 more
core +1 more source