Results 81 to 90 of about 11,893,587 (282)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Design approach for optimization of a piston ring profile considering mixed lubrication

open access: yesFriction, 2016
To reduce the friction of a piston ring while maintaining a large oil film load-carrying capacity, an approach comprising of the inverse method and the sequential quadratic programming algorithm was proposed. The approach considers the variation of mixed
Zhinan Zhang, Jun Liu, Youbai Xie
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

An inverse method for radiation transport

open access: yesRadiation Protection Dosimetry, 2005
Adjoint functions have been used with forward functions to compute gradients in implicit (iterative) solution methods for inverse problems in optical tomography, geoscience, thermal science and other fields, but only once has this approach been used for inverse solutions to the Boltzmann transport equation.
J A, Favorite, R, Sanchez
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Approximation of Non-Linear Stress–Strain Curve for GFRP Tensile Specimens by Inverse Method

open access: yesApplied Sciences, 2019
Studying the characteristics of materials through a finite element analysis (FEA) has various benefits; hence, many studies have been conducted to improve the reliability of the analysis results.
Dong Seok Shin   +2 more
doaj   +1 more source

Influence of aging on mechanical properties of the femoral neck using an inverse method. [PDF]

open access: yesBone Rep, 2022
Voumard B   +4 more
europepmc   +1 more source

The Inverse Fast Multipole Method

open access: yesCoRR, 2014
This article introduces a new fast direct solver for linear systems arising out of wide range of applications, integral equations, multivariate statistics, radial basis interpolation, etc., to name a few. \emph{The highlight of this new fast direct solver is that the solver scales linearly in the number of unknowns in all dimensions.} The solver ...
Sivaram Ambikasaran, Eric Darve
openaire   +2 more sources

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

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