An introduction to inverse probability of treatment weighting in observational research [PDF]
ABSTRACTIn this article we introduce the concept of inverse probability of treatment weighting (IPTW) and describe how this method can be applied to adjust for measured confounding in observational research, illustrated by a clinical example from nephrology. IPTW involves two main steps. First, the probability—or propensity—of being exposed to the risk
Chesnaye, Nicholas C +6 more
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Comparison of Dynamic Treatment Regimes via Inverse Probability Weighting [PDF]
Abstract: Appropriate analysis of observational data is our best chance to obtain answers to many questions that involve dynamic treatment regimes. This paper describes a simple method to compare dynamic treatment regimes by artificially censoring subjects and then using inverse probability weighting (IPW) to adjust for any selection bias introduced by
Miguel A, Hernán +3 more
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Accurate treatment effect estimation using inverse probability of treatment weighting with deep learning. [PDF]
Abstract Objectives Observational data have been actively used to estimate treatment effect, driven by the growing availability of electronic health records (EHRs). However, EHRs typically consist of longitudinal records, often introducing time-dependent confounding that hinder the unbiased estimation
Lee J, Ma S, Serban N, Yang S.
europepmc +3 more sources
Inverse probability of treatment weighting with generalized linear outcome models for doubly robust estimation [PDF]
There are now many options for doubly robust estimation; however, there is a concerning trend in the applied literature to believe that the combination of a propensity score and an adjusted outcome model automatically results in a doubly robust estimator and/or to misuse more complex established doubly robust estimators. A simple alternative, canonical
Erin E. Gabriel +6 more
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Background This study compared the efficacy and safety between catheter‐directed thrombolysis (CDT) and systemic thrombolysis for patients with acute pulmonary embolism (PE) with midterm follow‐up.
Donna Shu‐Han Lin +4 more
doaj +1 more source
The influence of maternal migration on child vaccination in Kenya: An inverse probability of treatment-weighted analysis [PDF]
Kenya has substantially improved child mortality between 1990 and 2019, with under-5 mortality decreasing from 104 to 43 deaths per 1000 live births. However, only two-thirds of Kenyan children receive all recommended vaccines by 1 year, making it essential to identify undervaccinated subpopulations. Internal migrants are a potentially vulnerable group
Julia M. Porth +4 more
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Propensity Score Methods in Rhinologic Observational Research: Principles, Applications, Extensions, and Practical Considerations [PDF]
Randomized controlled trials (RCTs) remain the gold standard for evaluating treatment efficacy because randomization minimizes measured and unmeasured confounding.
Jae Hoon Cho
doaj +1 more source
Time‐varying effect of sex on prognosis of lung adenocarcinoma surgical patients in China
Background Little is known about the prognostic advantage of sex for pulmonary adenocarcinoma among Chinese patients. In this study, we aimed to investigate the true sex differences in prognosis by adjusting for confounders and to explore whether the ...
Zezhou Wang +9 more
doaj +1 more source
Approaches to inverse-probability-of-treatment–weighted estimation with concurrent treatments
Objectives: In a setting with two concurrent treatments, inverse-probability-of-treatment weights can be used to estimate the joint treatment effects or the marginal effect of one treatment while taking the other to be a confounder. We explore these two approaches in a study of intravenous iron use in hemodialysis patients treated concurrently with ...
Ellis, Alan R., Brookhart, M. Alan
openaire +2 more sources
Splenic hilar lymph node dissection enhances survival in Bormann type 4 gastric cancer
Splenic hilar (no.10) lymph node dissection during total gastrectomy is no longer recommended for advanced proximal gastric cancer. However, the treatment efficacy of no.10 lymph node dissection in Borrmann type 4 tumors remains unclear.
Oh Jeong +3 more
doaj +1 more source

