Results 31 to 40 of about 35,653 (239)

Inversion of Gamow’s formula and inverse scattering

American Journal of Physics, 2006
Gamow’s tunneling formula is inverted and the issue of the uniqueness of the solution is compared with the solution obtained by the method of Gel’fand and Levitan. Some insight is gained into the key differences between classical and quantum inverse scattering, which account for the fact that a potential can be uniquely determined in the latter but ...
Gandhi, Sohang C., Efthimiou, Costas J.
openaire   +4 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Remarks on the Phaseless Inverse Uniqueness of a Three-Dimensional Schrödinger Scattering Problem

Advances in Mathematical Physics, 2016
We consider the inverse scattering theory of the Schrödinger equation. The inverse problem is to identify the potential scatterer by the scattered waves measured in the far-fields.
Lung-Hui Chen
doaj   +1 more source

A Generative Deep Learning Approach for Shape Recognition of Arbitrary Objects from Phaseless Acoustic Scattering Data

Advanced Intelligent Systems, 2023
A generative deep learning approach for shape recognition of an arbitrary object from its acoustic scattering properties is proposed and demonstrated.
Waqas W. Ahmed, Mohamed Farhat, Pai-Yen Chen, Xiangliang Zhang, Ying Wu   +4 more
doaj   +1 more source

Hybrid Method for Inverse Elastic Obstacle Scattering Problems

Mathematics, 2023
The problem of determining the shape of an object from knowledge of the far-field of a single incident wave in two-dimensional elasticity was considered. We applied an iterative hybrid method to tackle this problem. An advantage of this method is that it
Yuhan Yin, Juan Liu
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Photon yield of superradiant inverse Compton scattering from microbunched electrons

New Journal of Physics, 2022
Compact x-ray sources offering high-brightness radiation for advanced imaging applications are highly desired. We investigate, analytically and numerically, the photon yield of superradiant inverse Compton scattering from microbunched electrons in the ...
B H Schaap, T D C de Vos, P W Smorenburg, O J Luiten   +3 more
doaj   +1 more source