Results 61 to 70 of about 688,784 (301)

Cálculo de Parámetros Hipocentrales Mediante el Método de Inversión Generalizada

open access: yesRevista de Investigación de Física, 2017
En este trabajo se aplicó el método de inversión generalizada para calcular los parámetros hipocentrales de eventos sísmicos de origen local y regional a partir de la lectura del tiempo de arribo de las fases P y S de al menos 4 estaciones sísmicas.
César Jiménez, Daniel Olcese
doaj   +1 more source

InversionNet: An Efficient and Accurate Data-Driven Full Waveform Inversion [PDF]

open access: yesIEEE Transactions on Computational Imaging, 2018
Full-waveform inversion problems are usually formulated as optimization problems, where the forward-wave propagation operator $f$ maps the subsurface velocity structures to seismic signals.
Yue Wu, Youzuo Lin
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

EL BNDES DE LA SUSTITUCIÓN DE IMPORTACIONES AL NEOLIBERALISMO. UNA EXPLICACIÓN MARXISTA

open access: yesRevista de Economía, 2015
Después de funcionar de manera exitosa durante la época de sustitución de importaciones —incrementando los niveles de producción y del empleo—; en el neoliberalismo, muchos bancos de desarrollo han sido desmantelados o cambiado radicalmente sus funciones.
Victor Manuel Isidro Luna
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Análisis estratégico de la gestión sostenible del patrimonio cultural del Centro Histórico de Santa Ana de Coro, Falcón, Venezuela

open access: yesÁgora de Heterodoxias, 2020
La gestión sostenible del patrimonio cultural representa un conjunto de procesos llevados a cabo por los actores sociales del Centro Histórico de Santa Ana de Coro, en el abordaje científico se describen las problemáticas y los componentes que las median,
Viviam Gotía-Molina   +2 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Parafunciones y caries dentales en preescolares de comunidades pehuenches

open access: yesRevista Cubana de Estomatología, 2012
Introducción: las parafunciones bucales son consideradas uno de los factores causales de los trastornos temporomandibulares que han tomado mucha relevancia en las últimas décadas, especialmente en poblaciones infanto-juveniles, aunque la evidencia en ...
Ricardo Cartes-Velásquez   +2 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Power sector: institutional framework, issues, and new trends

open access: yesThēmis, 2016
The power sector of a country is highly relevant for its competitiveness and social development. In Peru, this sector has passed through many changes before having its current configuration, which has negative and positive aspects. In the present versus,
Maria Teresa Quiñones Alayza   +1 more
doaj  

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