Results 51 to 60 of about 153,277 (261)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The composite effect reveals that human (but not other primate) faces are special to humans.
PLoS ONE, 2023 Recognising faces is widely believed to be achieved using "special" neural and cognitive mechanisms that depend on "holistic" processing, which are not used when recognising other kinds of objects.
Danielle Sulikowski +4 more
doaj +1 more source
Microscopic Theory of the Inverse Edelstein Effect [PDF]
Physical Review Letters, 2014 We provide a precise microscopic definition of the recently observed inverse Edelstein effect in which a nonequilibrium spin accumulation in the plane of a two-dimensional (interfacial) electron gas drives an electric current perpendicular to its own direction.
Shen K, Vignale G, RAIMONDI, Roberto
openaire +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Journal of Foot and Ankle Research, 2014 Background There is still uncertainty concerning the beneficial effects of shoe collar height for ankle sprain prevention and very few data are available in the literature regarding the effect of high‐top and low‐top shoes on muscle responses during ...
Weijie Fu, Ying Fang, Yu Liu, Jianfu Hou
doaj +1 more source
Motion can amplify the face-inversion effect [PDF]
Psihologija, 2011 The face-inversion effect (FIE) refers to increased response times or error rates for faces that are presented upside-down relative to those seen in a canonical, upright orientation. Here we report one situation in which this FIE can be amplified when
Thornton Ian M. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
IEEE Transactions on Neural Systems and Rehabilitation EngineeringFaces and bodies provide critical cues for social interaction and communication. Their structural encoding depends on configural processing, as suggested by the detrimental effect of stimulus inversion for both faces (i.e., face inversion effect - FIE ...
Francesco Bossi +2 more
doaj +1 more source
Inversion of Stokes profiles with systematic effects [PDF]
Astronomy & Astrophysics, 2016 11 pages, 5 figures, accepted for publication in A& ...
Ramos, A. Asensio +3 more
openaire +2 more sources