Results 91 to 100 of about 5,164 (176)

Reduced Mechanical Tactile Stimulation Under Space Microgravity Affects Synaptic Signaling and Contributes to Neuromuscular Aging in Caenorhabditis elegans

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Microgravity (μG) reduces mechanical tactile stimulation in Caenorhabditis elegans, causing neuromuscular decline, altered gene expression, synaptic defects, and accelerated aging phenotypes. The gentle‐touch mechanoreceptor MEC‐4 mediates μG‐induced body length reduction and extracellular matrix gene downregulation.
Atsushi Higashitani, Je‐Hyun Moon, Jong‐In Hwang, Nahoko Higashitani, Toko Hashizume, Ahmad Aisha Abu, Kazuki Ooizumi, Ibuki Sazuka, Yoshimitsu Hashizume, Masumi Umehara, Alfredo V. Alcantara Jr, Ban‐seok Kim, Timothy Etheridge, Nathaniel J. Szewczyk, Takaaki Abe, Jin I. Lee, Akira Higashibata   +16 more
wiley   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

DHEA inhibits regeneration in <i>Lumbriculus variegatus</i>. [PDF]

MicroPubl Biol
Frank E, Pardue I, Rahman I, Banthin E, Gillen K.   +4 more
europepmc   +1 more source

Evolution of Insulin, Insulin-like Growth Factors, and Their Cognate Receptors in Vertebrates, Invertebrates, and Viruses. [PDF]

Mol Biol Evol
Chrudinová M, DaCosta JM, Dogru D, Huang R, Reiners R, De Meyts P, Altindis E.   +6 more
europepmc   +1 more source

Gene Expression of <i>GqBursicon</i> in <i>Gynaephora qinghaiensis</i> (Lepidoptera: Lymantriidae) and Its Impact on Wing Expansion. [PDF]

Int J Mol Sci
Kou G, Zhou Y, Liu Z, Wang H, Zhao Y, Li R, Lai Y, Gao S.   +7 more
europepmc   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective. [PDF]

Biol Rev Camb Philos Soc
Pinto PIS, Miglioli A, LaLone CA, Baumann L, Baynes A, Blanc-Legendre M, Cancio I, Cousin X, Dang Z, Dumollard R, Ford AT, Green C, Iguchi T, Kearney P, Knigge T, Minier C, Monsinjon T, Monteiro MS, Sturve J, Watanabe H, Yamamoto H, Ankley G, Power DM, Katsiadaki I.   +23 more
europepmc   +1 more source

Decoding Neuropeptide Complexity: Advancing Neurobiological Insights from Invertebrates to Vertebrates through Evolutionary Perspectives. [PDF]

ACS Chem Neurosci
Fields L, Dang TC, Tran VNH, Ibarra AE, Li L.   +4 more
europepmc   +1 more source

How resistance-nodulation-division (RND) efflux pumps contribute to virulence. [PDF]

PLoS Pathog
Detweiler CS, Alav I.
europepmc   +1 more source

Endocrine Disruption in Freshwater Cladocerans: Transcriptomic Network Perspectives on TBOEP and PFECHS Impacts in <i>Daphnia magna</i>. [PDF]

Int J Mol Sci
Kim HW, Yun SG, Park JY, Lee J, Han JP, Shin DY, Lee JH, Cho EM, Seo YR.   +8 more
europepmc   +1 more source