Results 41 to 50 of about 21,062 (233)

Feeding and the rhodopsin family G-Protein Coupled Receptors (GPCRs) in nematodes and arthropods

Frontiers in Endocrinology, 2012
In vertebrates, receptors of the rhodopsin G-protein coupled superfamily (GPCRs) play an important role in the regulation of feeding and energy homeostasis and are activated by peptide hormones produced in the brain-gut axis.
Joao Carlos dos Reis Cardoso, Rute Castelo Felix, Vera Garcia Fonseca, Deborah Mary Power   +3 more
doaj   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Identification of Thyroid Hormones and Functional Characterization of Thyroid Hormone Receptor in the Pacific Oyster Crassostrea gigas Provide Insight into Evolution of the Thyroid Hormone System.

PLoS ONE, 2015
Thyroid hormones (THs) play important roles in development, metamorphosis, and metabolism in vertebrates. During the past century, TH functions were regarded as a synapomorphy of vertebrates.
Wen Huang, Fei Xu, Tao Qu, Rui Zhang, Li Li, Huayong Que, Guofan Zhang   +6 more
doaj   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]

, 2010
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
core   +1 more source

Induced hyperlipaemia and immune challenge in locusts [PDF]

, 2004
Injections of immunogens, such as β-1,3-glucan or lipopolysaccharide (LPS), bring about a marked hyperlipaemia with associated changes in lipophorins and apolipophorin-III in the haemolymph of Locusta migratoria.
Ashida, Ashida, Brehelin, Candy, Cheeseman, Dettloff, Dettloff, Dunphy, Flanigan, Gillespie, Goldsworthy, Goldsworthy, Goldsworthy, Goldsworthy, Goldsworthy, Goldsworthy, Goldsworthy, Graham J. Goldsworthy, Harlow, Harthoorn, Jomori, Jutsum, Kawasaki, Kodrik, Lee, Lisa M. Mullen, Ma, Mary E. Lightfoot, Mullen, Mwangi, Oudejans, Oudejans, Schacterle, Soderhall, Strand, Wang, Whitten, Wiesner, Zakarian, Ziegler   +39 more
core   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Reconstructing life‐time reproductive histories using steroid hormones in cephalopod beaks

Limnology and Oceanography Letters
Reproductive data are vital for fisheries and conservation management. For cephalopods, reproductive data are usually obtained by analyzing gonads, which only provide data on an individual at a given time and require whole deceased specimens.
Erica D. Durante, Michael D. Wiese, Ashley S. Meakin, Karina C. Hall, Zoë A. Doubleday   +4 more
doaj   +1 more source

Walrus Odobenus rosmarus research in Svalbard, Norway, 2000-2010

NAMMCO Scientific Publications, 2014
Herein we report results from studies on walruses in Svalbard conducted in 2000-2010. Data from newly developed satellite relay data loggers (SRDLs) revealed seasonal differences in habitat use of adult male walruses. During winter, they moved into areas
Christian Lydersen, Kit M Kovacs
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source