Results 91 to 100 of about 3,867,281 (278)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Fast Dictionary-Based Compression for Inverted Indexes

open access: yesProceedings of the Twelfth ACM International Conference on Web Search and Data Mining, 2019
Dictionary-based compression schemes provide fast decoding operation, typically at the expense of reduced compression effectiveness compared to statistical or probability-based approaches. In this work, we apply dictionary-based techniques to the compression of inverted lists, showing that the high degree of regularity that these integer sequences ...
Pibiri G. E., Petri M., Moffat A.
openaire   +4 more sources

HII: Histogram Inverted Index For Fast Images Retrieval [PDF]

open access: yes, 2018
This work aims to improve the speed of search by creating an indexing structure in CBIR system. We utilised an inverted index structure that usually used in text retrieval with a modification.
Eko Minarno, Agus   +3 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Adding Compression to Block Addressing Inverted Indexes

open access: yesInformation Retrieval, 2000
Inverted index compression, block addressing and sequential search on compressed text are three techniques that have been separately developed for efficient, low-overhead text retrieval. Modern text compression techniques can reduce the text to less than 30% of its size and allow searching it directly and faster than the uncompressed text.
Gonzalo Navarro 0001   +4 more
openaire   +4 more sources

Inverted index compression based on term and document identifier reassignment [PDF]

open access: yes, 2008
Cataloged from PDF version of article.Includes bibliographical references leaves 43-46.Compression of inverted indexes received great attention in recent years. An inverted index consists of lists of document identifiers, also referred as posting lists,
Baykan, İzzet Çağrı
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Gertrude Inverted Topologies

open access: yes, 2005
Inverted Topology is an artist group who produce site-specific artworks collectively. The group is engaged with conceptual methodologies that were first explored in the early 20th century through constructivist and geometric practices.
Jenkins, Kyle
core   +1 more source

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