Results 81 to 90 of about 54,684 (305)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Modeling and Control of Inverter Zero-Voltage-Switching for Inductive Power Transfer System
IEEE Access, 2019 It's very important to maintain the inverter zero-voltage-switching(ZVS) for inductive power transfer (IPT) system, especially for those high power applications. The ZVS condition can be obtained via regulating the inverter operating frequency of the IPT
Jiangtao Liu +3 more
doaj +1 more source
Error-power tradeoffs in QCA design [PDF]
, 2008 In this work we present an error-power tradeoff study in a Quantum-dot Cellular Automata (QCA) circuit design. Device parameter variation to optimize performance is a very crucial step in the development of a technology.
Bhanja, S., Sarkar, S., Srivastava, S.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
“Desain dan Analisa Bidirectional Inverter sebagai Penggerak Mesin Induksi Satu Fasa dengan Sumber Baterai DC 36 Volt ” [PDF]
, 2016 Increasing oil prices and global warming, many people think to developed energy technology. One of them is the bidirectional DC-DC / DC-AC converter. Bidirectional that mean the converter can work in both directions.
\u27, N. (Nurhalim) +2 more
core
RDG System in Remote Areas with Utility or Local Feed Topology and Operation Strategy [PDF]
, 2014 In remote regions with availability of wind energy, a RDG (renewable distributed generation) system is an advantageous alternative to increase the provision of electrical supply.
Battaiotto, Pedro Eduardo +3 more
core +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
DC Link Voltage Control of Enhanced Bidirectional Z Source Inverter with Improved ADＲC
Journal of Harbin University of Science and Technology, 2020 An improved auto disturbance rejection control technique ( ADＲC) is proposed to control the DC link voltage of the enhanced bidirectional Z source inverter. Firstly，the basic working principle of the enhanced bidirectional Z-source inverter is introduced，
YAN Jing-bin +4 more
doaj +1 more source
A Practical Model and an Optimal Controller for Variable Speed Wind Turbine Permanent Magnet Synchronous Generator [PDF]
, 2017 The aim of this paper is the complete modeling and simulation of an optimal control system using practical setup parameters for a wind energy conversion system (WECS) through a direct driven permanent magnet synchronous generator (D-PMSG) feeding ac ...
Cossar, Calum +2 more
core +1 more source
Invertible Residual Rescaling Models
Invertible Rescaling Networks (IRNs) and their variants have witnessed remarkable achievements in various image processing tasks like image rescaling. However, we observe that IRNs with deeper networks are difficult to train, thus hindering the representational ability of IRNs.
Li, Jinmin +8 more
openaire +2 more sources