Results 101 to 110 of about 23,565,951 (358)

Spatio-Temporal Assessment of Urban Carbon Storage and Its Dynamics Using InVEST Model

open access: yesLand
Carbon storage estimates are essential for sustainable urban planning and development. This study examines the spatio-temporal effects of land use and land cover changes on the provision and monetary value of above- and below-ground carbon sequestration ...
Richa Sharma   +5 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Predicting the aesthetic impact of wind turbines and their influence on landscape value

open access: yesTeMA: Journal of Land Use, Mobility and Environment
The growing reliance on renewable energy sources (RES) is a direct response to global challenges such as climate change and the limited availability of fossil fuels.
Shiva Rahmani   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Modeling Aggregate Investment: A Fundamentalist Approach [PDF]

open access: yesFinance and Economics Discussion Series, 2003
This paper applies some lessons from recent estimation of investment models with firm-level data to the aggregate data with an eye to rehabilitating convex costs of adjusting the capital stock. In recent firm-level work, the response of investment to output and other "fundamental" variables is interpreted in terms of ...
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Spatiotemporal Evolution of Carbon Storage in the Central Yunnan Urban Agglomeration and Its Response to LULC Change

open access: yesShuitu Baochi Xuebao
[Objective] This paper aims to deepen the understanding of the carbon cycle by analyzing the spatiotemporal evolution characteristics of carbon storage in the central Yunnan urban agglomeration and its response to land use/land cover (LULC) change, so as
PENG Shuangyun   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Analysis of Landscape Patterns and Spatio-temporal Evolution of Habitat Quality in the PU River Basin Based on the InVEST Model

open access: yesShuitu Baochi Xuebao
[Objective] Through the spatio-temporal dynamic analysis of landscape ecological pattern and habitat quality, the response of habitat quality before and after the implementation of soil and water conservation measures in PU River Basin of Shenyang City ...
LIU Jiayi, XU Dawei, XU Jia
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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