Results 11 to 20 of about 630,811 (133)

Enzymatically Synthesized Poly(Gallic Acid) Modulates Methionine Synthase Activity and Neuroblastoma Morphology in Contrast to Phthalate-Type Endocrine Disruptors. [PDF]

open access: yesBiopolymers
ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
García-Cerón G   +7 more
europepmc   +2 more sources

Functional Effects of Prebiotic Fructans in Colon Cancer and Calcium Metabolism in Animal Models

open access: yesBioMed Research International, Volume 2017, Issue 1, 2017., 2017
Inulin‐type fructans are polymers of fructose molecules and are known for their capacity to enhance absorption of calcium and magnesium, to modulate gut microbiota and energy metabolism, and to improve glycemia. We evaluated and compared the effects of Chicory inulin “Synergy 1®” and inulin from Mexican agave “Metlin®” in two experimental models of ...
Marisol Rivera-Huerta   +9 more
wiley   +1 more source

Disfunción ejecutiva en la Enfermedad de Huntington en fase preclínica versus fase clínica

open access: yesRevista Clínica Escuela de Medicina UCR-HSJD, 2019
La Enfermedad de Huntington ha sido estudiada mayoritariamente por su sintomatología motora, pero las afecciones cognitivas y psiquiátricas aparecen años antes del debut motor.
Milena Radulovich Muñoz   +2 more
semanticscholar   +1 more source

Anticonvulsant and Toxicological Evaluation of Parafluorinated/Chlorinated Derivatives of 3‐Hydroxy‐3‐ethyl‐3‐phenylpropionamide

open access: yesBioMed Research International, Volume 2016, Issue 1, 2016., 2016
Although the anticonvulsant activity of 3‐hydroxy‐3‐ethyl‐3‐phenylproionamide (HEPP) is well‐known, its use is limited by the pharmacotoxicological profile. We herein tested its fluorinated and chlorinated derivatives (F‐HEPP and Cl‐HEPP) with two seizure models, maximal electroshock seizures (MES), and intraperitoneal pentylenetetrazole (PTZ ...
Osvaldo Garrido-Acosta   +7 more
wiley   +1 more source

Underscreened Women Remain Overrepresented in the Pool of Cervical Cancer Cases in Spain: A Need to Rethink the Screening Interventions

open access: yesBioMed Research International, Volume 2015, Issue 1, 2015., 2015
Objective. Audit of women with invasive cervical cancer (CC) is critical for quality control within screening activities. We analysed the screening history in the 10 years preceding the study entry in women with and without CC during 2000–2011. Methods. 323 women with CC from six pathology departments in Catalonia (Spain) and 23,782 women with negative
Raquel Ibáñez   +9 more
wiley   +1 more source

Vacunas contra COVID19. Una carrera contra el tiempo

open access: yesRevista médica de Panamá, 2020
La enfermedad conocida con el nombre de COVID19 y su agente etiológico SARSCoV2 fueron identificados a finales del año 2019 en la provincia de Wuhan, China y rápidamente notificados al mundo prontamente después. La pandemia, declarada por la OMS el 11 de
X. Sáez-Llorens
semanticscholar   +1 more source

Xanthium strumarium L. Extracts Produce DNA Damage Mediated by Cytotoxicity in In Vitro Assays but Does Not Induce Micronucleus in Mice

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Xanthium strumarium L. is a member of the Asteraceae commonly used in Cuba, mainly as diuretic. Some toxic properties of this plant have also been reported and, to date, very little is known about its genotoxic properties. The present work aims was to evaluate the potential cytotoxic and genotoxic risk of whole extract from Xanthium strumarium L. whole
Janet Piloto Ferrer   +14 more
wiley   +1 more source

Anemia falciforme y la resistencia a la malaria. Revisión narrativa

open access: yesRevista de la Facultad de Ciencias de la Salud Universidad del Cauca, 2020
La enfermedad de células falciformes (SCD, por sus siglas en inglés) es una hemoglobinopatía autosómica recesiva, producida por la mutación del gen de la cadena β-globina que genera la sustitución de valina por el ácido glutámico en la posición del sexto
Mariana Roldán-Isaza   +3 more
semanticscholar   +1 more source

Investigación preclínica en animales. Pautas actuales //Preclinical animal research. Current guidelines

open access: yesRevista de la Asociacion Odontologica Argentina
El uso de animales en experimentación científica está regulado por normativas diseñadas para garantizar la ética y el bienestar de los animales. A nivel mundial las regulaciones varían, pero muchos países como Argentina adoptan directrices establecidas ...
C. Bozal, C. A. Bárcenas
semanticscholar   +1 more source

Evaluación preclínica de la seguridad y la eficacia de la terapia con celulas madre mesenquimales para su utilización en un ensayo clínico en pacientes con neuropatía óptica isquémica anterior no arterítica

open access: yes, 2017
Se trata de un proyecto de investigacion de translacion en el area de Oftalmologia, que plantea el desarrollo de un nuevo tratamiento, basado en las denominadas terapias avanzadas, para pacientes que sufren neuropatia optica isquemica anterior no ...
Sonia Labrador-Velandia
semanticscholar   +1 more source

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