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Mesenchymal Stem Cell-Based Therapies in the Post-Acute Neurological COVID Syndrome: Current Landscape and Opportunities [PDF]

open access: yesBiomolecules, 2023
One of the main concerns related to SARS-CoV-2 infection is the symptoms that could be developed by survivors, known as long COVID, a syndrome characterized by persistent symptoms beyond the acute phase of the infection.
Lilia Carolina León-Moreno   +9 more
doaj   +2 more sources

Infection Mechanism of SARS-COV-2 and Its Implication on the Nervous System [PDF]

open access: yesFrontiers in Immunology, 2021
In late December 2019, multiple atypical pneumonia cases resulted in severe acute respiratory syndrome caused by a pathogen identified as a novel coronavirus SARS-CoV-2.
Edwin Estefan Reza-Zaldívar   +7 more
doaj   +2 more sources

A Simple, Safe, and Effective Method for Preparing Autologous Bio-Based Fibrin Glue for Ophthalmic Use [PDF]

open access: yesPharmaceutics, 2022
This study proposes a method to prepare autologous bio-based fibrin glue (FG) for use in ophthalmic surgery. FGs containing three fibrinogen concentrations and a thrombin concentrate were prepared using human blood from five donors (FG1: physiological ...
Luis Fernández-Vega-Cueto   +10 more
doaj   +2 more sources

Prevention of Teratogenesis in Pregnancies of Obese Rats by Vitamin E Supplementation [PDF]

open access: yesAntioxidants, 2021
Congenital malformations are a common adverse outcome in pregnancies complicated by pregestational obesity, although the underlying mechanisms are still unrevealed.
Martin Alcala   +9 more
doaj   +2 more sources

Particles Containing Cells as a Strategy to Promote Remyelination in Patients With Multiple Sclerosis [PDF]

open access: yesFrontiers in Neurology, 2020
The repair of demyelinated lesions is a key objective in multiple sclerosis research. Remyelination fundamentally depends on oligodendrocyte progenitor cells (OPC) reaching the lesion; this is influenced by numerous factors including age, disease ...
Jorge Matías-Guiu   +7 more
doaj   +2 more sources

Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing [PDF]

open access: yesiScience
Summary: ADAM29 (a disintegrin and metalloprotease domain 29) is a member of the membrane-anchored ADAM family of proteins, which is highly expressed in testis and may mediate different physiological and pathological processes.
Diana Campos-Iglesias   +4 more
doaj   +2 more sources

Contextualismo sexual

open access: yesAnálisis Filosófico, 2022
En este artículo se desarrolla el marco conceptual del “contextualismo sexual” para el estudio de las variables relacionadas con el sexo en la investigación biomédica.
Sarah S. Richardson
doaj   +1 more source

Aspectos bioéticos de la investigación preclínica para la evaluación farmacológica del suplemento nutricional LECISAN®

open access: yesRevista Iberoamericana de Bioética, 2023
Siempre deben buscarse técnicas alternativas al uso de animales para el avance del conocimiento científico, pero cuando estas no existan, o las existentes no sean lo suficientemente eficaces, debemos contar con la experimentación animal adoptando una ...
Leidys Cala-Calviño, Lianne Dunán Cala
doaj   +1 more source

A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1

open access: yesFrontiers in Cellular Neuroscience, 2020
Alzheimer’s disease (AD) is a chronic brain disorder characterized by progressive intellectual decline and memory and neuronal loss, caused mainly by extracellular deposition of amyloid-β (Aβ) and intracellular accumulation of hyperphosphorylated tau ...
Mercedes A. Hernández-Sapiéns   +5 more
doaj   +1 more source

Novel Sulfone 2-Aminobenzimidazole Derivatives and Their Coordination Compounds: Contribution of the Ethyl and Phenyl Substituents on Non-Covalent Molecular Interactions; Biological Antiproliferative Activity

open access: yesInorganics, 2023
New sulfone 2-aminobenzimidazole derivatives were designed and synthesized. Their nickel(II), copper(II), zinc(II), cadmium(II) and mercury(II) compounds were obtained and fully characterized by spectroscopic and analytical techniques.
David Colorado-Solís   +4 more
doaj   +1 more source

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