Results 11 to 20 of about 180 (99)

Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer’s Disease

open access: yesFrontiers in Cellular Neuroscience, 2018
Alzheimer’s disease (AD) is the most common type of dementia affecting regions of the central nervous system that exhibit synaptic plasticity and are involved in higher brain functions such as learning and memory.
Edwin E. Reza-Zaldivar   +6 more
doaj   +1 more source

Ortho-coumaric acid derivatives with therapeutic potential in a three-dimensional culture of the immortalised U-138 MG glioblastoma multiforme cell line

open access: yesNeurology Perspectives, 2022
Introduction: The treatment of such primary brain tumours such as glioblastoma multiforme (GBM) presents numerous difficulties, considerably impacting patient survival rates.
Y.K. Gutiérrez Mercado   +9 more
doaj   +1 more source

La eritropoyetina humana recombinante reduce la disfunción sensoriomotora y el deterioro cognitivo en ratas con enfermedad renal crónica

open access: yesNeurología, 2020
Resumen: Introducción: La enfermedad renal crónica (ERC) puede provocar anemia e inducir afectaciones neurológicas. La eritropoyetina humana recombinante (rHuEPO) se utiliza en el tratamiento de la anemia en la ERC. Sin embargo, existe poca evidencia de
E.E. Reza-Zaldívar   +7 more
doaj   +1 more source

Human recombinant erythropoietin reduces sensorimotor dysfunction and cognitive impairment in rat models of chronic kidney disease

open access: yesNeurología (English Edition), 2020
Introduction: Chronic kidney disease (CKD) can cause anaemia and neurological disorders. Recombinant human erythropoietin (rHuEPO) is used to manage anaemia in CKD.
E.E. Reza-Zaldívar   +7 more
doaj   +1 more source

Functional Effects of Prebiotic Fructans in Colon Cancer and Calcium Metabolism in Animal Models

open access: yesBioMed Research International, Volume 2017, Issue 1, 2017., 2017
Inulin‐type fructans are polymers of fructose molecules and are known for their capacity to enhance absorption of calcium and magnesium, to modulate gut microbiota and energy metabolism, and to improve glycemia. We evaluated and compared the effects of Chicory inulin “Synergy 1®” and inulin from Mexican agave “Metlin®” in two experimental models of ...
Marisol Rivera-Huerta   +9 more
wiley   +1 more source

Anticonvulsant and Toxicological Evaluation of Parafluorinated/Chlorinated Derivatives of 3‐Hydroxy‐3‐ethyl‐3‐phenylpropionamide

open access: yesBioMed Research International, Volume 2016, Issue 1, 2016., 2016
Although the anticonvulsant activity of 3‐hydroxy‐3‐ethyl‐3‐phenylproionamide (HEPP) is well‐known, its use is limited by the pharmacotoxicological profile. We herein tested its fluorinated and chlorinated derivatives (F‐HEPP and Cl‐HEPP) with two seizure models, maximal electroshock seizures (MES), and intraperitoneal pentylenetetrazole (PTZ ...
Osvaldo Garrido-Acosta   +7 more
wiley   +1 more source

Underscreened Women Remain Overrepresented in the Pool of Cervical Cancer Cases in Spain: A Need to Rethink the Screening Interventions

open access: yesBioMed Research International, Volume 2015, Issue 1, 2015., 2015
Objective. Audit of women with invasive cervical cancer (CC) is critical for quality control within screening activities. We analysed the screening history in the 10 years preceding the study entry in women with and without CC during 2000–2011. Methods. 323 women with CC from six pathology departments in Catalonia (Spain) and 23,782 women with negative
Raquel Ibáñez   +9 more
wiley   +1 more source

Xanthium strumarium L. Extracts Produce DNA Damage Mediated by Cytotoxicity in In Vitro Assays but Does Not Induce Micronucleus in Mice

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Xanthium strumarium L. is a member of the Asteraceae commonly used in Cuba, mainly as diuretic. Some toxic properties of this plant have also been reported and, to date, very little is known about its genotoxic properties. The present work aims was to evaluate the potential cytotoxic and genotoxic risk of whole extract from Xanthium strumarium L. whole
Janet Piloto Ferrer   +14 more
wiley   +1 more source

Cáncer gástrico, actualidades y perspectivas del futuro

open access: yesRevista Clínica de la Escuela de Medicina UCR-HSJD, 2016
El cáncer gástrico es una de las causas de muerte más importantes a nivel mundial, pese al descenso de la incidencia y mortalidad sigue siendo un pro-blema de salud pública importante.
Hebel Solano Muñoz   +1 more
doaj   +1 more source

Potential of Chitosan and Its Derivatives for Biomedical Applications in the Central Nervous System

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
It is well known that the central nervous system (CNS) has a limited regenerative capacity and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of biomaterials has emerged as an alternative to overcome these limitations.
Doddy Denise Ojeda-Hernández   +4 more
doaj   +1 more source

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