Results 111 to 120 of about 3,670,839 (240)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Marijuana eradication report, 2001
, 2004 Separate reports are generated for indoor and outdoor ...
Kansas Bureau of Investigation
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Ohio Bureau of Criminal Investigation
"Dave Yost, Attorney General"; "Protecting the Unprotected"; "Created: 3/1/2024 ..."--Document properties screen; Palm card.Laboratory Division -- Investigations Division -- Identification Division -- OHLEG DivisionThe Ohio Attorney General’s Bureau of ...
core
, 2015 Palm card.; "Mike DeWine, Ohio Attorney General."; "Created: 11/6/2015..."--Document properties screen.; "Protecting Ohio's Families."; Harvested from the web on 11/9/15How to get involved -- Benefits -- Qualifications -- How to sign up.The Ohio Child ...
core
Enquêter sur nos attachements. Comment hériter de William James ?
Sociologies, 2015 This paper aims neither to assimilate pragmatism into the social sciences, nor to claim that the two are totally divergent: it merely raises the question of the social survey.
Antoine Hennion
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
[History of the Kansas Bureau of Investigation]
, 1989 application/pdf; Title supplied by cataloger.Introduction -- Building the Image: the First Year -- K-Men Doing Good Job -- Building the Bureau: 1940 ...
Kansas Bureau of Investigation.
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source