FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Case Report: Alectinib and CNS-directed therapy for primary or relapsed ALK-positive anaplastic large cell lymphoma with central nervous system involvement. [PDF]
Front OncolMikalonytė M +16 more
europepmc +1 more source
The Confidence Database Investigator Adjunct Investigator Adjunct Investigator
Understanding how people rate their confidence is critical for characterizing a wide range of perceptual, memory, motor, and cognitive processes. However, as in many other fields, progress has been slowed by the difficulty of collecting new data and the unavailability of existing data.
Dobromir Rahnev +9 more
openaire +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Complementary efficacy of CD127-directed immunotherapy with lusvertikimab and ABL-targeting tyrosine kinase inhibitors in preclinical ABL-class-fusion-positive B-ALL. [PDF]
HemaspherePinkle D +35 more
europepmc +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
A One Health investigation of a Crimean-Congo Hemorrhagic fever outbreak reveals high seropositivity in livestock in Lyantonde District, Uganda, 2024. [PDF]
One HealthNyakarahuka L +14 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Age- and sex-specific incidence rates and future projections for hip fractures in The Gambia, West Africa, and comparison across four countries in Africa. [PDF]
J Bone Miner ResWilson H +12 more
europepmc +1 more source