Results 141 to 150 of about 3,853,799 (198)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Silicon carbonate, Si[CO₃]₂, is a potential carbon host in the deep Earth. [PDF]

Sci Adv
Spahr D, Bayarjargal L, Kovalev V, Sharapova N, Brüning L, Jurzick PL, Sebastian SS, Bykov M, Milman V, Glazyrin K, Bykova E, Winkler B.   +11 more
europepmc   +1 more source

Genome sequences of 19 <i>Klebsiella</i> phages of the genus <i>Przondovirus</i>. [PDF]

Microbiol Resour Announc
Peters TL, Urick CD, Ward AM, Burke KA, Braverman JL, Koert MT, Kirillina OA, Mzhavia N, Nikolich MP, Filippov AA.   +9 more
europepmc   +1 more source

Design and rationale of the RISC-trial: multicentre <i>R</i>CT to assess <i>i</i>mmediate discharge of <i>s</i>yncope patients admitted to the (<i>c</i>ardiac) emergency room. [PDF]

Eur Heart J Open
Boel TT, Peeters SYG, van Alem AP, Boogers MJ, Bootsma M, van den Dorpel MA, Firouzi M, Groothuis JGJ, Hemels MEW, Houtgraaf JH, Jansen WPJ, de Jong JSY, Jongenotter M, Kaal ECA, Koomen EM, Langerak SE, Mairuhu G, Mullaart NE, van Rees JB, Samim M, Wierda E, van Zanten S, van Zoelen A, van Barreveld M, Croon PM, Dijkgraaf MGW, Tijssen JGP, De Groot JR, de Lange FJ.   +28 more
europepmc   +1 more source

[Editorial: Investigation--investigators].

Actas dermo-sifiliograficas, 1976
openaire   +1 more source