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Studi Kasus Pelaksanaan Investigasi Kecelakaan di PT. Swastisiddhi Amagra Pekanbaru Tahun 2021
, 2022 Accidents are possible. However, these accidents can be prevented by conducting accident investigations. Accident investigation is important because in order to analyze accidents that have occurred so as to reduce the potential for the same accident to ...
Simamora, Eliza Betha Meilanie
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
How to Develop Meta-Cognitionto Thinking Process in Order to Improve Investigation Skill [PDF]
Journal of Systemics, Cybernetics and Informatics, 2006 In this paper a special way to use intelligence tests in order to strengthen the student teachers' meta-cognition and their ability to master the skills was examined.
Esther Zaretsky, Varda Bar
doaj
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Order from New Mexico Governor Antonio de Otermin, for an investigation of the conduct of some of the Spanish refugee settlers at San Lorenzo, El Paso, who refused to received their pay from the King of Spain, with various declarations.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The dynamic interaction of order flows and the CAD/USD exchange rate [PDF]
We explore the relationship between disaggregated order flow, the Canada/U.S. dollar (CAD/USD) market and U.S. macroeconomic announcements. Three types of CAD order flow and the CAD/USD are cointegrated.
Christopher J. Neely, Nikola Gradojevic
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
European Investigation Order and Joint Investigation Team
Law Journal of New Bulgarian UniversityThe present work is a comparative analysis between the EIO and the JIT, which is valuable from a theoretical point of view. Understanding the legal nature and functions of the EIO and the JIT – their points of contact, strengths and weaknesses – is essential for creating a clearer vision of the current legal mechanisms for international cooperation in ...
openaire +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source