Results 191 to 200 of about 205,670 (312)

Triple-Negative Breast Cancer Brain Metastasis: A Comprehensive Review of Epidemiology, Molecular Pathobiology, and Therapeutic Frontiers. [PDF]

Cancers (Basel)
Yang H, Zhao Y, Wang Y, Ma X, Ling J, Zeng X, Li Z, Liao G.   +7 more
europepmc   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

Journal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou, Ting Chen, Ying Huang, Huali Wang, Dahai He, Feng Wu, Yan Zhang, Lirui Kong   +7 more
wiley   +1 more source

From phase 1 to approval: lymphoma's long road. [PDF]

Blood Adv
Hertzberg M.
europepmc   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

A randomized controlled trial of home‐applied dual‐light photodynamic therapy during supportive periodontal care (HOPE‐CP study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a common, chronic inflammatory disease that relies heavily on effective daily oral hygiene for long‐term control. Light‐based therapies have demonstrated strong antibacterial potential; however, their effectiveness in regular home use remains unexplored.
Saila Pakarinen, Hannamari Välimaa, Anna M. Heikkinen, Marja Noponen, Heikki Alapulli, Riitta K. T. Saarela, Taina Tervahartiala, Ismo T. Räisänen, Timo Sorsa, Dimitra Sakellari, Tommi Pätilä   +10 more
wiley   +1 more source

Telemedicine as a gateway to early-phase oncology trials: lessons from 14 000 patients and future directions for global access and equity. [PDF]

Oncologist
Torrado C, Andersen CR, Kang L, Brink AL, Adesoye T, Le H, Patterson CJ, Poullard A, Osburn JA, Tan HN, Gouda MA, Charles S, Urschel GE, Tang TY, Hong DS, Champiat S, Naing A, Tsimberidou AM, Dumbrava EE, Piha-Paul SA, Rodon J, Yap TA, Pohlmann PR, Meric-Bernstam F, Fu S.   +24 more
europepmc   +1 more source

Cytoreductive Surgery in Patients With Metastatic Succinate Dehydrogenase‐Deficient Gastrointestinal Stromal Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Succinate dehydrogenase‐deficient (SDH‐deficient) gastrointestinal stromal tumors (GIST) are characterized by variable disease biology with poor responses to traditional tyrosine kinase inhibitors. The role of surgical intervention has been highly debated.
Katherine Y. Chen, Mark Antkowiak, Ashwyn K. Sharma, Robert Mallory, Adam M. Burgoyne, Paul T. Fanta, Jason K. Sicklick   +6 more
wiley   +1 more source

Improving Laboratory-Based Cancer Drug Discovery Study Designs for Better Research Translations. [PDF]

Methods Protoc
Manoharan S.
europepmc   +1 more source

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong, Richard Watchorn, Sandra Jerkovic Gulin, Christopher B. Bunker, Georgios Kravvas   +4 more
wiley   +1 more source

Case Report: PTCH1 splice-site mutation and sonidegib treatment in Gorlin-Goltz syndrome: clinical insights from a family case study. [PDF]

Front Med (Lausanne)
Liu L, Du H, Wang N, Lv S, Yu C, Deng L.
europepmc   +1 more source