Results 231 to 240 of about 205,670 (312)

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Regulatory, ethical, and clinical barriers to exosome use in interventional pain medicine. [PDF]

Interv Pain Med
Bourcier AJ, Kirkor ZM.
europepmc   +1 more source

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source

Correction: Opportunities for and Challenges of Pulmonary Drug Delivery in the Management of Acute Exacerbations of CNS Disorders. [PDF]

CNS Drugs
Detyniecki K, Strzelczyk A, Roebling R, Laloyaux C, Chanteux H, Cloyd JC.   +5 more
europepmc   +1 more source

Repeatability of Metabolic Imaging With Hyperpolarized Pyruvate: Back‐to‐Back Neuroimaging and Blood Analysis

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose 13C MRI with hyperpolarized [1‐13C]pyruvate enables noninvasive imaging of metabolic pathways. Considering the high dose of pyruvate used in hyperpolarized 13C‐pyruvate studies, circulating 13C‐pyruvate and the resulting 13C‐lactate in plasma may influence subsequent pyruvate metabolism, yet the guidance on consecutive injections does ...
Jun Chen, Sung‐Han Lin, Jessica Sudderth, Kelley A. Derner, Crystal E. Harrison, Maheen Zaidi, Jeannie D. Baxter, Jeff Liticker, Zohreh Erfani, Craig R. Malloy, Marco C. Pinho, Ralph J. DeBerardinis, Jae Mo Park   +12 more
wiley   +1 more source

Development of a standard operating procedure for investigational product rights of administration in clinical trials. [PDF]

J Clin Transl Sci
Hill L, Jones CT.
europepmc   +1 more source

Shear Wave Elastography to Assess Respiratory Muscle Function in Congenital Myopathies

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Respiratory muscle dysfunction is prevalent in congenital myopathies and often leads to respiratory failure. Ultrasound shear wave elastography (SWE) measures tissue elasticity and has been proposed as an alternative to invasive measures of respiratory muscle contractility.
J. L. M. van Doorn, D. Jans, C. L. de Korte, B. G. M. van Engelen, N. C. Voermans, N. van Alfen, C. A. C. Ottenheijm, D. Bachasson, J. Doorduin   +8 more
wiley   +1 more source

Prospective Open-Label Safety Study of Edaravone Dexborneol in Filipino Patients With Acute Ischemic Stroke. [PDF]

Brain Behav
Sabellano ZF, Pedregosa B, Batino LK, Navarro J.   +3 more
europepmc   +1 more source

Phenotyping Overactive Bladder—Part 1: Are There Different Types of Urgency and Can They be Translated to Clinical, Urodynamic and Radiological Phenotyping? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Overactive bladder (OAB) is defined as urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urgency urinary incontinence (OAB‐wet) or without (OAB‐dry), in the absence of urinary tract infection or other detectable disease.
John E. Speich, D. Carolina Ochoa, Pradeep Tyagi, Apostolos Apostolidis, Sanjay Sinha, Claire Hentzen, Marcus Drake, Paul Abrams, Alan J. Wein, Michel Wyndaele   +9 more
wiley   +1 more source

Navigating Drug-Drug Interactions in Clinical Drug Development: A Tutorial. [PDF]

Clin Transl Sci
Lohy Das J, Ajavon-Hartmann AT, Schmith VGD.   +2 more
europepmc   +1 more source