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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source
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An Investigation of an Action of Penicillin

Nature, 1957
PREVIOUS work1 has suggested that amiphenazole (2 : 4-diamino-5-phenylthiazole hydrochloride, ‘Daptazole’, ‘DHA 245’) may enter, after a period of delay (1–3 weeks), into the thiamine metabolism of weanling rats maintained on a thiamine-free diet.
A, SHULMAN, M I, DICK, K T, FARRER
openaire   +2 more sources

INVESTIGATIVE EXPERIMENT IN THE SYSTEM OF INVESTIGATIVE ACTIONS

ЖУРНАЛ ПРАВОВЫХ И ЭКОНОМИЧЕСКИХ ИССЛЕДОВАНИЙ, 2023
В статье рассмотрены особенности производства следственного эксперимента, его значение, отличие от других схожих следственных действий, осуществляемых в рамках расследования уголовного дела. Раскрыты особенности и порядок проведения следственного эксперимента на разных стадиях уголовного процесса.
openaire   +1 more source

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