Results 11 to 20 of about 18,913,418 (345)
The Lancet Rheumatology, 2021 BACKGROUND Systemic sclerosis is a connective tissue disease characterised by multiorgan fibrosis with an autoimmune background and poor prognosis. Although a few drugs have shown some efficacy in treating the disease, there remains a great unmet medical
S. Ebata +14 more
semanticscholar +1 more source
HemaSphere, 2022 Acalabrutinib is a Bruton tyrosine kinase inhibitor approved for patients with chronic lymphocytic leukemia (CLL). ASCEND is the pivotal phase 3 study of acalabrutinib versus investigator’s choice of idelalisib plus rituximab (IdR) or bendamustine plus ...
P. Ghia +17 more
semanticscholar +1 more source
Validation of the Hidradenitis Suppurativa Investigator Global Assessment
JAMA dermatology, 2023 Key Points Question Is the Hidradenitis Suppurativa Investigator Global Assessment (HS-IGA) a valid end-point measure for clinical trials in patients with hidradenitis suppurativa (HS?) Findings In this secondary analysis of the UCB phase 2 randomized ...
A. Garg +10 more
semanticscholar +1 more source
Investigator-initiated trials of targeted oncology agents: why independent research is at risk?
, 2013 Background: Drug development traditionally has relied upon the complementary contributions of clinicians and scientists at academic institutions and at pharmaceutical companies.
S. Embacher-Aichorn (17258512) +10 more
core +5 more sources
British Journal of Dermatology, 2022 The validated Investigator Global Assessment for Atopic Dermatitis (vIGA‐AD™) is a standardized severity assessment for use in clinical trials and registries for atopic dermatitis (AD).
E. Simpson +11 more
semanticscholar +1 more source
Investigator Racial Diversity and Clinical Trial Participation
, 2023 We investigate whether increased racial diversity of clinical trial principal investigators could increase the enrollment of Black patients, which currently lags population and disease-burden shares.
Leister, Lukas +3 more
core +1 more source
The Physician-Investigator Workforce: Looking Ahead.
Academic medicine : journal of the Association of American Medical Colleges, 2021 Support of the U.S. health professions investigator workforce is critically important to the continued advancement of health care nationally. Physician-investigators comprise one segment of this health professions investigator workforce, which also ...
Dorothy A. Andriole, R. Wolfson
semanticscholar +1 more source
The Criminal Investigator [PDF]
, 2009 [Extract]“One should always look for a possiblealternative and provide against it.It is the first rule of criminal investigation. It isof the highest importance in the art of detectionto be able to recognise, out of a number offacts, which are incidental
Goldsworthy, Terrence; id_orcid
core +5 more sources
Oral Oncology, 2018 Objectives We report 2-year results from CheckMate 141 to establish the long-term efficacy and safety profile of nivolumab and outcomes by tumor PD-L1 expression in patients with recurrent or metastatic (R/M),platinum-refractory squamous cell carcinoma ...
R. Ferris +20 more
semanticscholar +1 more source
The Lancet Oncology, 2015 Summary Background Patients with melanoma that progresses on ipilimumab and, if BRAFV600 mutant-positive, a BRAF or MEK inhibitor or both, have few treatment options.
A. Ribas +35 more
semanticscholar +1 more source