Results 41 to 50 of about 658,410 (316)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

DDX-BRO Investigator Brochure v1.1

open access: yes, 2023
<p>Investigator Brochure v1.1 of the DDX-BRO study</p ...
Marcin, Thimo
core   +1 more source

Investigator-initiated trials of targeted oncology agents: why independent research is at risk?

open access: yes, 2013
Background: Drug development traditionally has relied upon the complementary contributions of clinicians and scientists at academic institutions and at pharmaceutical companies.
S. Embacher-Aichorn (17258512)   +10 more
core   +1 more source

Investigation protocol: Acromegaly and its investigation [PDF]

open access: yesClinical Endocrinology, 1999
The diagnosis of acromegalyAcromegaly is an uncommon but serious disease due to anexcessive production of growth hormone (GH), usually from apituitary tumour. Although it has an insidious onset, onceclinically suspected its diagnosis is not usually difficult.
Duncan E., Wass J.A.H.
openaire   +6 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Uropsilus investigator

open access: yes, 1993
Uropsilus investigator (Thomas, 1922). Ann. Mag. Nat. Hist., ser. 9, 10:393. TYPE LOCALITY: China, Yunnan, Kui-chiang-Salween divide at 28°N, 11,000 ft. DISTRIBUTION: Yunnan (China). COMMENTS: Hoffmann (1984) included investigator in gracilis but on
Rainer Hutterer
core   +1 more source

Incidence of herpes zoster and postherpetic neuralgia in Italian adults aged ≥50 years: A prospective study

open access: yesPreventive Medicine Reports, 2019
Herpes zoster (HZ) mainly affects older adults and immunocompromised individuals and is usually characterized by a unilateral painful skin rash. Its most common complication, postherpetic neuralgia (PHN), may cause chronic debilitating pain lasting for ...
Andrea Salvetti   +14 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Code Base Investigator v1.2.0

open access: yes
<p>Although a minor release, Code Base Investigator v1.2.0 includes a few significant changes.</p> <blockquote> <p><strong>IMPORTANT</strong><br>In previous releases of Code Base Investigator, the main script was
Douglas Jacobsen   +2 more
core   +1 more source

THE OBSTRUCTION OF THE ADMINISTRATION OF JUSTICE AND PRELIMINARY INVESTIGATION: PROBLEMS OF THE OBJECT AND THE OBJECTIVE SIDE

open access: yesПравоприменение, 2018
The subject. The article is devoted to the investigation of the main direct object and the circle of victims are subjected of harm by criminal acts stipulated by pts. 1, 2 of art.
A. V. Boyarskaya
doaj   +1 more source

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