Results 211 to 220 of about 18,913,418 (345)
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Research governance in England needs improvements to ensure participant and site confidentiality in healthcare workforce research. [PDF]
Aunger J +10 more
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
DeepLabCut-based automated system reveals diverse temperature tolerance among medaka strains and related Oryzias species. [PDF]
Matsuo Y +5 more
europepmc +1 more source
Nowadays, it would be difficult to imagine a person investigating a case individually, without coordination of actions with other subjects, especially when complex, multi-episodic cases are investigated. The efficiency of solved crimes, investigation and prevention partly depends on cooperation between prosecutors and investigators.
openaire +2 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
After a brief introduction to astronomy, stellar types and the Guest Investigator program for the Extreme Ultraviolet Explorer (EUVE) NASA satellite, students conduct a brief astrophysics lab.
core
The sponsor-proxy model: Bridging basic science discovery and investigator-initiated clinical trials. [PDF]
Liu X, Shank D, Lü J, Joshi M.
europepmc +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source

