Results 81 to 90 of about 497,399 (235)

Anti‐cancer drugs targeting the NADH‐binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity

open access: yesThe FEBS Journal, EarlyView.
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali   +6 more
wiley   +1 more source

EFEITO DA FLEXIBILIDADE NA DECISÃO DE INVESTIMENTO: UMA APLICAÇÃO À EXPLORAÇÃO DE COBRE [PDF]

open access: yes, 2002
Este estudo permite evidenciar o efeito da flexibilidade na decisão de investimento. Essa flexibilidade foi apelidada de opções reais, opções essas que possuem valor, o qual aumentará o valor de um investimento que as possua. Esta avaliação foi realizada
Gomes Santana Félix, Elisabete
core  

Sulphur‐mediated iron homeostasis in four tetraploid wheats (Triticum turgidum L.)

open access: yesPlant Biology, EarlyView.
Polish wheat's tolerance to S limitation enables a well‐orchestrated response for efficient Fe acquisition when S is scarce, involving increased Fe accumulation, enhanced phytosiderophore release, and upregulated TdIRO2 and TdYSL15 expression. Abstract Sulphur (S) deficiency is known to hinder iron (Fe) uptake and distribution in wheat, mainly by ...
E. Coppa   +6 more
wiley   +1 more source

Why foreign savings fail to cause growth [PDF]

open access: yes
Este artigo é uma formalização da crítica à estratégia do crescimento com poupança externa que um de seus autores vem sendo fazendo nos últimos anos.
Gala, Paulo Sérgio de Oliveira Simões   +1 more
core  

Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Left: Pre‐processing. First, we perform the segmentation of the Computer Tomography angiorgraphy (angio‐CT) scans of a healthy patient, obtaining the surface of a healthy thoracic aorta with a Type III aortic arch. Then, we build nine ideal configurations with Descending Thoracic Aortic Aneurysm (DTAA), varying the aortic arch ...
Francesca Duca   +7 more
wiley   +1 more source

Mudanças no padrão de financiamento do investimento no Brasil [PDF]

open access: yesBrazilian Journal of Political Economy
RESUMO O padrão de financiamento do investimento está mudando no Brasil. Durante a década de 70 baseou-se no padrão clássico que prevalece nas fases iniciais do desenvolvimento, ou seja, no financiamento estatal e externo.
LUIZ CARLOS BRESSER-PEREIRA
doaj   +1 more source

The importance of cash holdings for acquiring companies in mergers and acquisitions [PDF]

open access: yes, 2017
Dissertação de mestrado em FinançasCash holdings can be an important vehicle for firms to undertake value increasing investment opportunities, but also a source of agency costs.
Castanho, João Bento Ramos
core  

Enhanced Microbial Sensing via Resazurin Reduction Catalyzed by Graphene Oxide, A Versatile Approach for Diagnostics and Electrochemical Applications

open access: yesEnvironmental Toxicology, Volume 41, Issue 4, Page 223-232, April 2026.
ABSTRACT Resazurin is a cell viability phenoxazine dye widely employed for bacterial monitoring, as its colorimetric and fluorometric conversion reflects microbial metabolic activity. In this work, we demonstrate that graphene oxide (GO), a two‐dimensional nanomaterial with high surface reactivity, markedly accelerates the reduction of resazurin in the
Valentina Palmieri   +2 more
wiley   +1 more source

Grau de investimento e as perspectivas para a economia brasileira: uma análise b. luz da experiência de outros países [PDF]

open access: yes, 2008
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.0 presente trabalho trata das perspectivas do Brasil em virtude do recebimento da classificação de risco de grau de investimento pelas principais agências de risco
Ramon, Alexandre Greuel
core  

The FORGENIUS Genomic Resources: New Genotyping Tools and Genomic Data for 23 Forest Tree Species and Their Genetic Conservation Units

open access: yesMolecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Genetic diversity is a critical but often overlooked component of biological diversity. The European H2020 FORGENIUS project is aimed at increasing the quality and quantity of genetic data to start monitoring the European network of forest Genetic Conservation Units (GCUs).
Sara Pinosio   +78 more
wiley   +1 more source

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