Results 31 to 40 of about 1,467,737 (309)

Analysis and estimation of effectiveness of investment projects

Technology audit and production reserves, 2017
Analysis and general characteristics of international practice of existing methods for effectiveness evaluation of investment projects/programs are presented, and the rationale for making investment decisions regarding selected investment projects is presented. For the adoption of an optimal investment solution, there is a need to carry out preparatory
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Project financing in the investment and construction complex

Вестник университета, 2021
The problems arising in organizations during the process of investment activities have been considered. The results of financing and implementation of projects and programs have been analysed and interpreted consistently.
O. E. Astafieva, A. V. Kozlovsky, N. A. Moiseenko   +2 more
doaj   +1 more source

Value creation by Turkish enterprises [PDF]

, 2006
This study focuses on the resurgence of the automotive and appliance sectors in Turkey’s recent years. The analysis of both these sectors reveals some interesting lessons about technology management and investment strategies for companies to invest in ...
Altintas, Nihat, Altıntaş, Nihat, Kekre, Sunder, Sarpca, Elif B., Ulusoy, Gunduz, Ulusoy, Gündüz   +5 more
core   +1 more source

Investment analysis of Hungarian apple-orchard and fruit storage projects

International Journal of Horticultural Science, 2016
There are profound, long-term changes in world apple production and trade. The former hegemony of Europe in apple production doest not exists any more, among the most important apple exporters the emerging economies have a growing importance. The globalising apple market means new challenges of traditional producers. This is especially true for Hungary,
F. Apáti, Z. Lakner
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Optimal timing and capacity choice under the rate-of-return renewable energy support

MethodsX, 2020
This article presents a stylized renewable energy (RE) investment project profitability analysis under a rate-of-return RE support type. We use a dynamic programming approach to value the real options.
Mariia Kozlova, Stein-Erik Fleten, Verena Hagspiel   +2 more
doaj   +1 more source

Assessment of investment in electric buses: A case study of a public transport company

Open Engineering, 2021
This case study presents an assessment of the efficiency and risk of the vehicle fleet renewal in the public transport company. The investment project is solved in two alternatives.
Fabianova Jana, Janekova Jaroslava
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source