Results 41 to 50 of about 1,708,538 (309)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

PROJECT FINANCE AS A TOOL FOR THE IMPLEMENTATION OF INVESTMENT PROJECTS

open access: yesНаука Красноярья, 2015
The article discusses the reasons for the insufficient use of project financing in the Russian Federation, the brief historical background for the project financing in Russia, as well as the main principles, types and stages of project financing.
U. V. Vsyakih, V. E. Mikhaylovskaya
doaj   +1 more source

The influence of water vapor on the structural response of asphalt pavement

open access: yesScience and Engineering of Composite Materials, 2023
A series of water damage phenomena of asphalt pavement during service show that water is very important. To comprehensively analyze the influence of water vapor factors on the response of pavement structure, this article first tests the water vapor ...
Zhang Youhua   +3 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Company investment announcements and the market value of the firm [PDF]

open access: yes, 2004
This paper examines the stock market reaction to 402 company investment announcements made by UK companies during the 1991-1996 period. The market-adjusted abnormal returns are generally positive but small.
Danbolt, J., Hirst, I., Jones, E.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Risk assessment in investment project [PDF]

open access: yesОмский научный вестник: Серия "Общество. История. Современность", 2019
The purpose of the study is to analyze the existing methods of assessing risk and uncertainty when making decisions about investing, to illustrate the application of one of the considered methods, the Monte-Carlo method, and to analyze the results ...
A. L. Tkachenko, O. G. Sheveleva
doaj   +1 more source

Venture Capital and Sequential Investments [PDF]

open access: yes
We analyze sequential investment decisions in an innovative project that depend on the investor's information about the project failure risk and its potential final value. We consider the feedback effects between learning about the project parameters and
Dirk Bergemann, Liang Peng, Ulrich Hege
core   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

espida Brochure [PDF]

open access: yes, 2007
Brochure descibing the espida Project. The espida project has developed an approach to help the proposer and decision-maker (or funder) enter into an effective dialogue about the character of outcomes (be they positive or negative) that an investment
espida, espida,
core  

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