Results 41 to 50 of about 166,750 (266)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
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Risk assessment in investment project [PDF]
Омский научный вестник: Серия "Общество. История. Современность", 2019 The purpose of the study is to analyze the existing methods of assessing risk and uncertainty when making decisions about investing, to illustrate the application of one of the considered methods, the Monte-Carlo method, and to analyze the results ...
A. L. Tkachenko, O. G. Sheveleva
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Arthritis Care &Research, EarlyView.Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge +6 more
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RATES OF REAL INVESTMENT EFFICIENCY: EVOLUTION AND DIFFICULTIES OF USE
Вестник Российского экономического университета имени Г. В. Плеханова, 2017 The article investigates rates of investment efficiency and points to problems arising while comparing investment projects, which are different in scale and duration.
Svetlana P. Ivanova, Alexey N. Litvinov
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ASSESSMENT OF INVESTMENT DEMAND WITH REGARD TO REGIONAL SOCIOECONOMIC DEVELOPMENT [PDF]
Экономика региона, 2010 The authors of the present paper consider development of perception and estimation of the economic category “investment demand” of a region from the standpoint of its significance in reference to regional policy-making and investment process ...
А. I. Tatarkin, M. R. Bimatov
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Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
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The PRIMA Thesaurus for Materials Science and Engineering
Advanced Engineering Materials, EarlyView.The PRIMA Thesaurus is a structured vocabulary designed to improve how materials science data is described and shared. Developed with input from multiple experts, it enables clear documentation of research workflows, data exchange, and reuse across platforms.
Rossella Aversa +8 more
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Pathways for the Coordinated Development of Landscape Architecture and the Low-Altitude Economy
Fengjing YuanlinObjectiveThe low-altitude economy covers low-altitude manufacturing, flight operations, support services and comprehensive service industries, and has the characteristics of spatially three-dimensional, regional dependence, digital ecology, industrial ...
Yan WU, Suke WU, Zhiqiang ZHAO
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