Results 231 to 240 of about 17,882,248 (290)

Hyperledger Fabric for the (digitalized) lifecycle of construction products: Applied review on fastening technology

open access: yesCivil Engineering Design, Volume 7, Issue 1, Page 9-22, March 2025.
Abstract Blockchain technology is a digital decentralized data ledger recording transactions in an encrypted format. Its implementation can potentially hold significant advantages for the built environment, particularly in manufacturing and building product usage aligned with Building Information Modeling (BIM). This paradigm shift toward decentralized
Aileen Pfeil   +2 more
wiley   +1 more source

Comparison of modelling approaches for liquid fluidized beds

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract This study presents a comparison of three promising numerical models for the detailed simulation of liquid–solid fluidized bed. These models differ in their treatment of the solid phase, ranging from treating each particle individually to treating the collection of particles as a continuum.
Andreu Bernad‐Serra   +3 more
wiley   +1 more source

The Governance Gap: Democratizing Drug Development Through Decision Architecture

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner   +16 more
wiley   +1 more source

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

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